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Benefits of homeopathic complementary treatment in breast cancer patients. A retrospective cohort.

Abstract : Introduction: There is a growing use of complementary therapy in oncology and homeopathy features prominently. Their purpose is to help patients better cope with the illness and the side effects (SEs) of cancer treatments that particularly affect quality of life (HRQOL). However, there are few comparative studies. The objective of this study is to assess the benefits of homeopathy treatment on the HRQOL for patients with non-metastatic breast cancer (BC), prescribed in post-surgical complementary therapy, compared to treatment without homeopathy. Methods: An extraction from the French nationwide healthcare database targeted all patients who underwent mastectomy for newly diagnosed BC during 2012-2013. HRQOL was assessed through proxies, primarily the use of medication palliating the SEs of cancer treatments. Exposure to homeopathy and use of SEs medication were measured by the number of dispensing. The association was assessed using a Random Effect Poisson Count Model, with adjustment for co-factors. Results: 98,009 patients were included (mean age 61.1). Patients taking homeopathy appeared to have less cardiovascular and diabetes comorbidities. Usage of homeopathy was observed in 11% of patients 7-12 months before surgery, 26% during the 6 months before surgery, 22% during the 6 months after, 18% 7-12 months after, then stable at 15% for 4 years. During the six months after surgery, there was a significant overall decrease (RR=0.88, CI95=[0.87; 0.89]) in the dispensing of SEs medication for patients with ?3 homeopathy dispensing vs. none. Decrease appeared to be greater for immunostimulants (RR=0.79, CI95=[0.74; 0.84]), corticosteroids (RR=0.82, CI95=[0.79; 0.85]), antidiarrheals (RR=0.83, CI95=[0.77; 0.88]), systemic antifungals (RR=0.86, CI95=[0.8; 0.92]), and antiemetics (RR=0.9, CI955=[0.87; 0.93]). Conclusion: The study showed a rising use of homeopathy by patients with BC, starting with diagnosis. This use was sustained after surgery and seemed to play an important role in helping to better tolerate SEs of cancer treatments.
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Submitted on : Wednesday, October 19, 2022 - 12:06:31 PM
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Mohammed Bennani, Jacques Medioni, Yecenia Lopez Marquez, Daniel Scimeca, Emmanuelle Leray, et al.. Benefits of homeopathic complementary treatment in breast cancer patients. A retrospective cohort.. European Journal of Integrative Medicine, 2021, 48, pp.101915. ⟨10.1016/j.eujim.2021.101915⟩. ⟨hal-03820857⟩



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