Impact of the COVID-19 pandemic on total, sex- and age-specific all-cause mortality in 20 countries worldwide during 2020: results from the C-MOR project - EHESP - École des hautes études en santé publique Access content directly
Journal Articles International Journal of Epidemiology Year : 2022

Impact of the COVID-19 pandemic on total, sex- and age-specific all-cause mortality in 20 countries worldwide during 2020: results from the C-MOR project

Souzana Achilleos
  • Function : Author
Annalisa Quattrocchi
  • Function : Author
John Gabel
  • Function : Author
Elena Critselis
  • Function : Author
Constantina Constantinou
  • Function : Author
Nicoletta Nicolaou
  • Function : Author
Giuseppe Ambrosio
  • Function : Author
Catherine Bennett
  • Function : Author
Julia Critchley
  • Function : Author
Laust Hvas Mortensen
  • Function : Author
Jose Manuel Rodriguez-Llanes
Mario Chong
  • Function : Author
Gleb Denissov
  • Function : Author
Petra Klepac
  • Function : Author
Lucy Goldsmith
  • Function : Author
Antonio José Leal Costa
  • Function : Author
Terje Hagen
  • Function : Author
Marie Chan Sun
  • Function : Author
Qian Huang
  • Function : Author
Nataliia Pidmurniak
  • Function : Author
Inbar Zucker
  • Function : Author
Joseph Cuthbertson
  • Function : Author
Bo Burström
  • Function : Author
Manuel Barron
  • Function : Author
Ivan Eržen
  • Function : Author
Fabrizio Stracci
  • Function : Author
Wilson Calmon
  • Function : Author
Cyndy Martial
  • Function : Author
Olesia Verstiuk
  • Function : Author
Zalman Kaufman
  • Function : Author
Wenjing Tao
  • Function : Author
Maia Kereselidze
  • Function : Author
Nino Chikhladze
  • Function : Author
Antonis Polemitis
  • Function : Author
Andreas Charalambous
  • Function : Correspondent author

Abstract

Background - To understand the impact of the COVID-19 pandemic on mortality, this study investigates overall, sex- and age-specific excess all-cause mortality in 20 countries, during 2020. Methods - Total, sex- and age-specific weekly all-cause mortality for 2015–2020 was collected from national vital statistics databases. Excess mortality for 2020 was calculated by comparing weekly 2020 observed mortality against expected mortality, estimated from historical data (2015–2019) accounting for seasonality, long- and short-term trends. Crude and age-standardized rates were analysed for total and sex-specific mortality. Results - Austria, Brazil, Cyprus, England and Wales, France, Georgia, Israel, Italy, Northern Ireland, Peru, Scotland, Slovenia, Sweden, and the USA displayed substantial excess age-standardized mortality of varying duration during 2020, while Australia, Denmark, Estonia, Mauritius, Norway, and Ukraine did not. In sex-specific analyses, excess mortality was higher in males than females, except for Slovenia (higher in females) and Cyprus (similar in both sexes). Lastly, for most countries substantial excess mortality was only detectable (Austria, Cyprus, Israel, and Slovenia) or was higher (Brazil, England and Wales, France, Georgia, Italy, Northern Ireland, Sweden, Peru and the USA) in the oldest age group investigated. Peru demonstrated substantial excess mortality even in the <45 age group. Conclusions - This study highlights that excess all-cause mortality during 2020 is context dependent, with specific countries, sex- and age-groups being most affected. As the pandemic continues, tracking excess mortality is important to accurately estimate the true toll of COVID-19, while at the same time investigating the effects of changing contexts, different variants, testing, quarantine, and vaccination strategies.
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Origin : Publication funded by an institution

Dates and versions

hal-03765388 , version 1 (01-06-2023)

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Christiana Demetriou, Souzana Achilleos, Annalisa Quattrocchi, John Gabel, Elena Critselis, et al.. Impact of the COVID-19 pandemic on total, sex- and age-specific all-cause mortality in 20 countries worldwide during 2020: results from the C-MOR project. International Journal of Epidemiology, 2022, ⟨10.1093/ije/dyac170⟩. ⟨hal-03765388⟩
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