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Pneumococcal serotype distribution among meningitis cases from Togo and Burkina Faso during 2007–2009

Abstract : We evaluated pneumococcal serotype/group distribution using polymerase chain reaction (PCR) testing on cerebrospinal fluid collected from patients from Burkina Faso and Togo who presented for care during 2007-2009. We identified 282 pneumococcal meningitis cases based on PCR, latex agglutination, or culture, of which 206 underwent serotyping. Serotype 1 was identified for 18% of serotyped cases from patients aged <5 years and 66% of those aged ≥5 years. The 13-valent and 10-valent pneumococcal conjugate vaccines (PCV-13 and PCV-10) contain 53% of serotypes identified among children age <5 years and 76-77% among persons aged ≥5 years. Pneumococcal meningitis was highly seasonal regardless of serotype. Data from this study emphasize the potential usefulness of PCVs among older children and adults.
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https://hal.ehesp.fr/hal-03034576
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Submitted on : Tuesday, December 1, 2020 - 6:23:40 PM
Last modification on : Wednesday, December 2, 2020 - 3:28:25 AM

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Bradford D Gessner, Oumarou Sanou, Aly Drabo, Tsidi Agbeko Tamekloe, Seydou Yaro, et al.. Pneumococcal serotype distribution among meningitis cases from Togo and Burkina Faso during 2007–2009. Vaccine, Elsevier, 2012, 30, pp.G41-G45. ⟨10.1016/j.vaccine.2012.10.052⟩. ⟨hal-03034576⟩

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