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Journal articles
Gender Differences in the Association between Socioeconomic Status and Subclinical Atherosclerosis
Abstract : Objectives
This study explored the pattern of associations between socioeconomic status (SES) and atherosclerosis progression (as indicated by carotid intima media thickness, CIMT) across gender.
Design
Cross-sectional analysis of a sample of 5474 older persons (mean age 73 years) recruited between 1999 and 2001 in the 3C study (France). We fitted linear regression models including neighborhood SES, individual SES and cardiovascular risk factors.
Results
CIMT was on average 24 µm higher in men (95% CI: 17 to 31). Neighborhood SES was inversely associated with CIMT in women only (highest versus lowest tertiles: −12.2 µm, 95%CI −22 to −2.4). This association persisted when individual SES and risk factors were accounted for. High individual education was associated with lower CIMT in men (−21.4 µm 95%CI −37.5 to −5.3) whereas high professional status was linked to lower CIMT among women (−15.7 µm 95%CI: −29.2 to −2.2). Adjustment for cardiovascular risk factors resulted in a slightly more pronounced reduction of the individual SES-CIMT association observed in men than in women.
Conclusion
In this sample, neighborhood and individual SES displayed different patterns of associations with subclinical atherosclerosis across gender. This suggests that the causal pathways leading to SES variations in atherosclerosis may differ among men and women.
https://hal.ehesp.fr/hal-02437437
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Submitted on : Wednesday, May 26, 2021 - 3:37:41 PM
Last modification on : Tuesday, March 15, 2022 - 9:39:06 AM
Long-term archiving on: : Friday, August 27, 2021 - 8:13:34 PM
Contributor : Scd Ehesp Connect in order to contact the contributor
Submitted on : Wednesday, May 26, 2021 - 3:37:41 PM
Last modification on : Tuesday, March 15, 2022 - 9:39:06 AM
Long-term archiving on: : Friday, August 27, 2021 - 8:13:34 PM
File
pone.0080195.pdf
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Licence
Distributed under a Creative Commons Attribution 4.0 International License