, Air quality guidelines for Europe. Copenhagen, WHO Regional Office for, European Series, issue.23, 1987.

, WHO Regional Office for, Air quality guidelines for Europe, 2000.

, Particulate matter, ozone, nitrogen dioxide and sulfur dioxide. Copenhagen, WHO Regional Office for, Europe, 2005.

, The right to healthy indoor air, pp.15-17, 2000.

, Development of WHO guidelines for indoor air quality, Report on a working group meeting, pp.23-24, 2006.

, WHO guidelines for indoor air quality: dampness and mould. Copenhagen, WHO Regional Office for, Europe, 2009.

, Principles for the assessment of risks to human health from exposure to chemicals. Geneva, World Health Organization, 1999.

, Evaluation and use of epidemiological evidence for environmental health risk assessment: WHO guideline document, Environmental Health Perspectives, vol.108, pp.997-1002, 2000.

, Damp indoor spaces and health, 2004.

, Mobile-source air toxics: a critical review of the literature on exposure and health effects, HEI Special Report, vol.16, 2007.

, Air quality guidelines for Europe, 2000.

, IEH report on the benzene in the environment. Leicester, MRC Institute for Environment and Health, 1999.

, IUPAC Subcommittee on Gas Kinetic Data Evaluation -Data Sheet HO x _AROM1, 2008.

, Environmental Health Criteria, vol.13, p.12, 1979.

K. Verschueren, Handbook of environmental data on organic chemicals, vol.1, p.24, 2001.

R. F. Coburn, R. E. Forster, and P. B. Kane, Considerations of the physiological variables that determine the blood carboxyhemoglo bin concentration in man, Journal of Clinical Investigation, vol.44, pp.1899-1910, 1965.

, Air quality criteria for carbon monoxide, 2000.

S. Alm, M. J. Jantunen, and M. Vartiainen, Urban commuter exposure to particle matter and carbon monoxide inside an automobile, Journal of Exposure Analysis and Environmental Epidemiology, vol.9, pp.237-244, 1999.

M. T. Kleinman, Environmental toxicants, human exposures and their health effects, Lippmann M, pp.499-528, 2009.

, International Programme on Chemical Safety. Carbon monoxide. Geneva, World Health Organization, vol.213, 1999.

J. Jetter, Characterization of emissions from burning incense, Science of the Total Environment, vol.295, pp.51-67, 2002.

M. Maroni, Air pollution exposure of adult population in Milan (Expolis Study), The 9th International Conference on Indoor Air Quality and Climate, vol.4, pp.455-460, 2002.

L. B. Georgoulis, Personal carbon monoxide exposure in five European cities and its determinants, Atmospheric Environment, vol.36, pp.963-974, 2002.

A. Chaloulakou, I. Mavroidis, and A. Duci, Indoor and outdoor carbon monoxide concentration relationships at different microenvironments in the Athens area, Chemosphere, vol.52, pp.1007-1019, 2003.

S. Alm, Personal carbon monoxide exposures of preschool children in Helsinki, Finland -comparison to ambient air concentrations, Atmospheric Environment, vol.35, pp.6259-6266, 2001.

G. Scotto-di-marco, Personal carbon monoxide exposure in Helsinki, Finland. Atmospheric Environment, vol.39, pp.2697-2707, 2005.

X. C. Pan, An evaluation of the indoor/outdoor air pollution and respiratory health of farmers living in rural areas of Anhui Province, China, The 9th International Conference on Indoor Air Quality and Climate, vol.4, pp.982-987, 2002.

F. Roughton, The equilibrium of carbon monoxide with human hemoglobin in whole blood, Annals of the New York Academy of Sciences, vol.174, pp.177-188, 1970.

F. Roughton and R. C. Darling, The effect of carbon monoxide on the oxyhemoglobin dissociation curve, American Journal of Physiology, vol.141, pp.17-31, 1944.

J. W. Severinghaus, Blood gas calculator, Journal of Applied Physiology, vol.21, pp.1108-1116, 1966.

V. A. Benignus, Prediction of carboxyhemoglobin formation due to transient exposure to carbon monoxide, Journal of Applied Physiology, vol.76, pp.1739-1745, 1994.

H. Hauck and M. Neuberger, Carbon monoxide uptake and the resulting carboxyhemoglobin in man, European Journal of Applied Physiology, vol.53, pp.186-190, 1984.

J. E. Peterson and R. D. Stewart, Absorption and elimination of carbon monoxide by inactive young men, Archives of Environmental Health, vol.21, pp.165-171, 1970.

J. E. Peterson and R. D. Stewart, Predicting carboxyhemoglobin levels resulting from carbon monoxide exposures, Journal of Applied Physiology, vol.39, pp.633-638, 1975.

M. V. Smith, Effect of regional circulation patterns on observed HbCO levels, Journal of Applied Physiology, vol.77, pp.1659-1665, 1994.

P. F. Tikuisis, F. Buick, and D. M. Kane, Percent carboxyhemoglobin in resting humans exposed repeatedly to 1,500 and 7,500 ppm carbon monoxide, Journal of Applied Physiology, vol.63, pp.820-827, 1987.

P. F. Tikuisis, A critical analysis of the use of the CFK equation in predicting COHb formation, American Industrial Hygiene Association Journal, vol.48, pp.208-213, 1987.

P. F. Tikuisis, Rate of formation of carboxyhemoglobin in exercising humans exposed to carbon monoxide, Journal of Applied Physiology, vol.72, pp.1311-1319, 1992.

M. L. Mccartney, Sensitivity analysis applied to the Coburn-Forster-Kane models of carboxyhemoglobin formation, American Industrial Hygiene Association Journal, vol.51, pp.169-177, 1990.

E. N. Bruce and M. C. Bruce, A multicompartment model of carboxyhemoglobin and carboxymyoglobin responses to inhalation of carbon monoxide, Journal of Applied Physiology, vol.95, pp.1235-1247, 2003.

E. N. Bruce, M. C. Bruce, and K. Erupaka, Prediction of the rate of uptake of carbon monoxide from blood by extravascular tissue, Respiratory Physiology and Neurobiology, vol.161, pp.142-159, 2008.

J. A. Raub and V. A. Benignus, Carbon monoxide and the nervous system, Neuroscience and Biobehavioral Reviews, vol.26, pp.925-940, 2002.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

M. A. Helfaer and R. J. Traystman, Cerebrovascular effects of carbon monoxide, pp.69-86, 1996.

P. Langston, The effects of carbon monoxide on oxygen metabolism in the brains in awake sheep, Toxicology, vol.114, pp.223-232, 1996.

M. D. Jones and R. J. Traystman, Cerebral oxygenation of the fetus, newborn and adult, Seminars in Perinatology, vol.8, pp.205-216, 1984.

R. C. Koehler, Comparison of cerebrovascular response to hypoxic and carbon monoxide hypoxia in newborn and adult sheep, Journal of Cerebral Blood Flow and Metabolism, vol.4, pp.115-122, 1984.

H. T. Millhorn, A mathematical model of the human respiratory control system, Biophysical Journal, vol.5, pp.27-46, 1965.

D. G. Penney, Chronic carbon monoxide poisoning, In: Penney DG, ed. Carbon monoxide toxicity, pp.393-418, 2000.

J. Raub, Carbon monoxide, 2nd ed. Geneva, World Health Organization, vol.213, 1999.

, The Index Project: critical appraisal of the setting and implementation of indoor exposure limits in the EU. Final report. Ispra, Joint Research Centre, 2005.

D. G. Penney, Carbon monoxide, 1996.

D. G. Penney, Carbon monoxide toxicity, 2000.

D. G. Penney, A challenge to the healthcare community: the diagnosis of carbon monoxide poisoning, Carbon monoxide poisoning, pp.437-448, 2008.

P. Tikuisis, Modeling the uptake and elimination of carbon monoxide, pp.45-68, 1996.

Q. Chen and L. Wang, Carbon monoxide air pollution and its health impact on the major cities of China, Carbon monoxide toxicity, pp.345-362, 2000.

P. G. Flachsbart, Exposure to ambient and microenvironmental concentrations of carbon monoxide, pp.5-42, 2008.

D. G. Penney, Effects of carbon monoxide exposure on developing animals and humans, pp.109-144, 1996.

S. R. White, Pediatric carbon monoxide poisoning, pp.463-492, 2000.

. Formaldehyde, In: Formaldehyde, 2-butoxyethanol and 1-tertbutoxypropan-2-ol. Lyon, International Agency for Research on Cancer, Evaluation of the Carcinogenic Risk of Chemicals to Humans, vol.88, pp.39-325, 2006.

D. R. Lide, CRC handbook of chemistry and physics, 1995.

K. Verschueren, Handbook of environmental data on organic chemicals, vol.1, p.24, 2001.

D. Mackay, Y. W. Shiu, and K. C. Ma, Illustrated handbook of physical-chemical properties and environmental fate for organic chemicals, 1992.

, Emergency standard guide for risk-based corrective action applied at petroleum release sites, 1995.

, Genium's handbook of safety, health, and environmental data for common hazardous substances, 1999.

Y. Su, Determination of octanol-air partition coefficients (KOA) values for chlorobenzenes and polychlorinated naphthalenes from gas chromatographic retention times, Journal of Chemical and Engineering Data, vol.47, pp.449-455, 2002.

F. Wania, Y. D. Lei, and T. Harner, Estimating octanol-air partition coefficients of nonpolar semivolatile organic compounds from gas chromatographic retention times, Analytical Chemistry, vol.74, pp.3476-3483, 2002.

, Hazardous Substances Data Bank (HSDB) [online database

M. D. Bethesda, , 2010.

R. Preuss, J. Angerer, and H. Drexler, Naphthalene -an environmental and occupational toxicant, International Archives of Occupational and Environmental Health, vol.76, pp.556-576, 2003.

M. J. Jantunen, Air pollution exposure in European cities: the EXPOLIS Study. Kuopio, National Public Health Institute, 1999.

K. Hoffmann, The German Environmental Survey 1990/1992 (GerES II): sources of personal exposure to volatile organic compounds, Journal of Exposure Analysis and Environmental Epidemiology, vol.10, pp.115-125, 2000.

K. Koistinen, The INDEX project: executive summary of a European Union project on indoor air pollutants, Allergy, vol.63, pp.810-819, 2008.

D. Kotzias, Final Report of the INDEX Project. Critical appraisal of the setting and implementation of indoor exposure limits in the EU, 2005.

R. D. Edwards, Personal exposures to VOC in the upper end of the distribution -relationships to indoor, outdoor and workplace concentrations, Atmospheric Environment, vol.39, pp.2299-2307, 2005.

W. E. Lambert, Nitrogen dioxide and respiratory illness in children. Part II. Assessment of exposure to nitrogen dioxide, vol.58, pp.33-50, 1993.

M. Simoni, The Po River Delta (north Italy) indoor epidemiological study: effects of pollutant exposure on acute respiratory symptoms and respiratory function in adults, Archives of Environmental Health, vol.57, pp.130-136, 2002.

O. Garcia-algar, Sources and concentrations of indoor nitrogen dioxide in, Journal of the Air & Waste Management Association, vol.53, pp.1312-1317, 2003.

, Committee on the Medical Effects of Air Pollutants. Guidance on the effects on health of indoor air pollutants. London, Department of Health, 2004.

, Air quality guidelines: global update 2005. Particulate matter, ozone, nitrogen dioxide and sulfur dioxide. Copenhagen, WHO Regional Office for Europe, 2006.

M. E. Hazenkamp-von-arx, PM 2.5 and NO 2 assessment in 21 European study centres of ECRHS II: annual means and seasonal differences, Atmospheric Environment, vol.38, pp.1943-1953, 2004.

Y. Kodama, Environmental NO 2 concentration and exposure in daily life along main roads in Tokyo, Environmental Research, vol.89, pp.236-244, 2002.

S. Nakai, H. Nitta, and K. Maeda, Respiratory health associated with exposure to automobile exhaust. II. Personal NO 2 exposure levels according to distance from the roadside, Journal of Exposure Analysis and Environmental Epidemiology, vol.5, pp.125-136, 1995.

N. Janssen, Assessment of exposure to traffic related air pollution of children attending schools near motorways, Atmospheric Environment, vol.35, pp.3875-3884, 2001.

J. D. Spengler, J. M. Samet, and J. F. Mccarthy, Indoor air quality handbook, 2001.

P. Blondeau, Relationship between outdoor and indoor air quality in eight French schools, Indoor Air, vol.15, pp.2-12, 2005.
URL : https://hal.archives-ouvertes.fr/hal-00312171

C. J. Weschler, Workgroup report: indoor chemistry and health, vol.114, pp.442-446, 2006.

M. Kattan, Health effects of indoor nitrogen dioxide and passive smoking on urban asthmatic children, Journal of Allergy & Clinical Immunology, vol.120, pp.618-624, 2007.

L. K. Baxter, Predictors of concentrations of nitrogen dioxide, fine particulate matter, and particle constituents inside of lower socioeconomic status urban homes, Journal of Exposure Science & Environmental Epidemiology, vol.5, pp.433-444, 2007.

C. Y. De-burbure, Lung permeability, antioxidant status, and NO 2 inhalation: a selenium supplementation study in rats, Journal of Toxicology and Environmental Health, Part A, vol.70, pp.284-294, 2007.

. Verein-deutscher-ingenieure, Maximale Immissions-Werte zum Schutze des Menschen: Maximale Immissions-Konzentrationen für Stickstoffdioxid [Maximum emission values for the protection of human health: maximum emission concentrations for nitrogen dioxide, VDI-Handbuch Reinhaltung der Luft, vol.1, 1985.

H. M. Wagner, Update of a study for establishing criteria (dose/effect relationships) for nitrogen oxides, 1985.

P. Rombout, Influence of exposure regimen on nitrogen dioxideinduced morphological changes in the rat lung, Environmental Research, vol.41, pp.466-480, 1986.

M. J. Evans, Transformation of alveolar Type 2 cells to Type 1 cells following exposure to NO 2, Experimental Molecular Pathology, vol.22, pp.142-150, 1975.

G. L. Snider, The definition of emphysema: report of a National Heart, Lung, and Blood Institute, Division of Lung Diseases workshop, American Review of Respiratory Disease, vol.32, pp.182-185, 1985.

G. B. Haydon, Nitrogen dioxide-induced emphysema in rabbits, American Review of Respiratory Disease, vol.95, pp.797-805, 1967.

G. Freeman, Covert reduction in ventilatory surface in rats during prolonged exposure to subacute nitrogen dioxide, American Review of Respiratory Disease, vol.106, pp.563-579, 1972.

D. Hyde, Morphometric and morphologic evaluation of pulmonary lesions in beagle dogs chronically exposed to high ambient levels of air pollutants, Laboratory Investigations, vol.38, pp.455-469, 1978.

R. E. Rasmussen, Effects of nitrogen dioxide on respiratory tract clearance in the ferret, Journal of Toxicology and Environmental Health, vol.41, pp.109-120, 1994.

M. Wegmann, NO 2 -induced airway inflammation is associated with progressive airflow limitation and development of emphysema-like lesions in C57bl/6 mice, Experimental and Toxicologic Pathology, vol.56, pp.341-350, 2005.

H. Fehrenbach, Nitrogen dioxide induces apoptosis and proliferation but not emphysema in rat lungs, Thorax, vol.62, pp.438-446, 2007.

F. J. Miller, Evaluating the toxicity of urban patterns of oxidant gases. II. Effects in mice from chronic exposure to nitrogen dioxide, Journal of Toxicology and Environmental Health, vol.21, pp.99-112, 1987.

C. E. Cuijpers, Adverse effects of the indoor environment on respiratory health in primary school children, Environmental Research, vol.68, pp.11-23, 1995.

C. Dekker, Childhood asthma and the indoor environment, Chest, vol.100, pp.922-926, 1991.

B. Hoelscher, Gas cooking, respiratory health and white blood cell counts in children, International Journal of Hygiene and Environmental Health, vol.203, pp.29-37, 2000.

R. E. Volkmer, The prevalence of respiratory symptoms in South Australian preschool children. II. Factors associated with indoor air quality, Journal of Paediatrics and Child Health, vol.31, pp.116-120, 1995.

B. P. Lanphear, Residential exposures associated with asthma in US children, Pediatrics, vol.107, pp.505-511, 2001.

A. Zacharasiewicz, Indoor factors and their association to respiratory symptoms suggestive of asthma in Austrian children aged 6-9 years, Wiener Klinische Wochenschrift, vol.111, p.1006, 1999.

G. M. Corbo, Effects of gas cooking in lung function in adolescents: modifying role of sex and immunoglobulin E, Thorax, vol.56, pp.536-540, 2001.

R. Chapman, W. Hadden, and S. Perlin, Influence of asthma and household environment on lung function in children and adolescents, American Journal of Epidemiology, vol.158, pp.175-189, 2003.

T. W. Wong, Household gas cooking: a risk factor for respiratory illnesses in preschool children, Archives of Disease in Childhood, vol.89, pp.631-636, 2004.

D. P. Strachan and I. M. Carey, Home environment and severe asthma in adolescence: a population based case-control study, BMJ, vol.311, pp.1053-1056, 1995.

A. L. Ponsonby, The relation between infant indoor environment and subsequent asthma: a prospective cohort study, Epidemiology, vol.11, pp.128-135, 2000.

A. L. Ponsonby, A prospective study of the association between home gas appliance use during infancy and subsequent dust mite sensitisation and lung function in childhood, Clinical & Experimental Allergy, vol.31, pp.1544-1552, 2001.

D. Bilderling and G. , Gas cooking and smoking habits and the risk of childhood and adolescent wheeze, American Journal of Epidemiology, vol.162, pp.513-522, 2005.

R. Mcconnell, Indoor risk factors for asthma in a prospective study of adolescents, Epidemiology, vol.13, pp.288-295, 2002.

C. S. Berkey, Indoor air pollution and pulmonary function growth in preadolescent children, American Journal of Epidemiology, vol.123, pp.250-260, 1986.

, Polycyclic organic matter (POM), 2007.

, Copenhagen, WHO Regional Office for, Air quality guidelines for Europe, 2000.

K. Srogi, Monitoring of environmental exposure to polycyclic aromatic hydrocarbons: a review, Environmental Chemistry Letters, vol.5, pp.169-195, 2007.

T. Ohura, Polycyclic Aromatic Hydrocarbons in indoor and outdoor environments and factors affecting their concentrations, Environmental Science & Technology, vol.38, pp.77-83, 2004.

P. Douben and E. , PAHs: an ecotoxicological perspective, 2003.

J. R. Boulding, EPA environmental assessment sourcebook, 1996.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

, Selected non-heterocyclic polycyclic aromatic hydrocarbons, International Programme on Chemical Safety, vol.202, 1998.

, Technical factsheet on: polycyclic aromatic hydrocarbons (PAHs)

, Position paper. Luxembourg, Office for Official Publications of the European Communities, p.20, 2001.

K. Nikolaou, Sources and chemical-reactivity of polynuclear aromatic hydrocarbons in the atmosphere -a critical-review, Science of the Total Environment, vol.32, pp.103-132, 1984.

S. O. Baek, A review of atmospheric polycyclic aromatic hydrocarbonssources, fate and behavior, Water, Air, and Soil Pollution, vol.60, pp.279-300, 1991.

L. Z. Zhu, Highly sensitive automatic analysis of polycyclic aromatic hydrocarbons in indoor and outdoor air, Talanta, vol.45, pp.113-118, 1997.

H. Fromme, Polycyclic aromatic hydrocarbons (PAH) and diesel engine emission (elemental carbon) inside a car and a subway train, Science of the Total Environment, vol.217, pp.165-173, 1998.

C. S. Li and Y. S. Ro, Indoor characteristics of polycyclic aromatic hydrocarbons in the urban atmosphere of Taipei, Atmospheric Environment, vol.34, pp.611-620, 2000.

S. Lung, Contribution of incense burning to indoor PM 10 and particle-bound polycyclic aromatic hydrocarbons under two ventilation conditions, Indoor Air, vol.13, pp.194-199, 2003.

C. Lau, Levels of selected organic compounds in materials for candle production and human exposure to candle emissions, Chemosphere, vol.34, pp.1623-1630, 1997.

A. Li, Polycyclic aromatic hydrocarbons in residential air of ten Chicago area homes: concentrations and influencing factors, Atmospheric Environment, vol.39, pp.3491-3501, 2005.

S. D. Dubowsky, The contribution of traffic to indoor concentrations of polycyclic aromatic hydrocarbons, Journal of Exposure Analysis and Environmental Epidemiology, vol.9, pp.312-321, 1999.

C. C. Tonne, Predictors of personal polycyclic aromatic hydrocarbon exposures among pregnant minority women in New York City, vol.112, pp.754-759, 2004.

P. Yc-l-i-c-a-r-o-m-at-i-c-h-y-d-r-o-c-a-r-b-o-n-s-20, Maliszewska-Kordybach B. Sources, concentrations, fate and effects of polycyclic aromatic hydrocarbons (PAHs) in the environment. Part A: PAHs in air, Polish Journal of Environmental Studies, vol.8, pp.131-136, 1999.

S. Tong and K. C. Lam, Home sweet home? A case study of household dust contamination in Hong Kong, Science of the Total Environment, vol.256, pp.115-123, 2000.

J. C. Chuang, Polycyclic aromatic-hydrocarbons and their derivatives in indoor and outdoor air in an 8-home study, Atmospheric Environment, vol.25, pp.369-380, 1991.

, Air quality guidelines for Europe. Copenhagen, WHO Regional Office for, European Series, issue.23, 1987.

S. Mitra and B. Ray, Patterns and sources of polycylic aromatic hydrocarbons and their derivatives in indoor air, Atmospheric Environment, vol.29, pp.3345-3356, 1995.

, The world health report 2002: reducing risks, promoting life. Geneva, World Health Organization, 2002.

S. V. Kakareka, Study of PAH emission from the solid fuels combustion in residential furnaces, Environmental Pollution, vol.133, pp.383-387, 2005.

S. Gupta, Emission factors and thermal efficiencies of cooking biofuels from five countries, Biomass & Bioenergy, vol.14, pp.547-559, 1998.

C. Venkataraman, Size distributions of polycyclic aromatic hydrocarbons in aerosol emissions from biofuel combustion, Journal of Aerosol Science, vol.33, pp.503-518, 2002.

Y. Ikarashi, Monitoring of polycyclic aromatic hydrocarbons and water-extractable phenols in creosotes and creosote-treated woods made and procurable in Japan, Chemosphere, vol.60, pp.1279-1287, 2005.

W. F. Rogge, Sources of fine organic aerosol .5. Natural-gas home appliances, Environmental Science & Technology, vol.27, pp.2736-2744, 1993.

N. Oanh, Emission of particulate matter and polycyclic aromatic hydrocarbons from select cookstove-fuel systems in Asia, Biomass & Bioenergy, vol.28, pp.579-590, 2005.

J. J. Schauer, Measurement of emissions from air pollution sources

, Environmental Science & Technology, vol.35, pp.1716-1728, 2001.

K. Ravindra, Atmospheric polycyclic aromatic hydrocarbons: source attribution, emission factors and regulation, Atmospheric Environment, vol.42, pp.2895-2921, 2008.

P. Gustafson, Indoor levels of polycyclic aromatic hydrocarbons in homes with or without wood burning for heating, Environmental Science & Technology, vol.42, pp.5074-5080, 2008.

A. L. Aggarwal, Assessment of exposure to benzo[a]pyrene in air for various population groups in Ahmedabad, Atmospheric Environment, vol.16, pp.867-870, 1982.

G. W. Traynor, Indoor air-pollution due to emissions from woodburning stoves, Environmental Science & Technology, vol.21, pp.691-697, 1987.

J. M. Daisey, A comparison of the organic-chemical composition of indoor aerosols during woodburning and nonwoodburning periods, Environment International, vol.15, pp.435-442, 1989.

C. Viau, Indoor exposure to polycyclic aromatic hydrocarbons and carbon monoxide in traditional houses in Burundi, International Archives of Occupational and Environmental Health, vol.73, pp.331-338, 2000.

B. J. Turpin, Relationships of indoor, outdoor and personal air (RIOPA)

I. I. Part, Analysis of concentrations of particulate matter species. Houston, TX, Health Effects Institute and National Urban Air Toxics Research Center, NUATRC Research Report, vol.10, 2007.

Y. Y. Naumova, Polycyclic aromatic hydrocarbons in the indoor and outdoor air of three cities in the US, Environmental Science & Technology, vol.36, pp.2552-2559, 2002.

J. C. Chuang, Methodology of ambient air monitoring for polycyclic aromatic hydrocarbons, Fresenius Environmental Bulletin, vol.8, pp.547-556, 1999.

S. Kingham, Spatial variations in the concentrations of traffic-related pollutants in indoor and outdoor air in Huddersfield, vol.34, pp.905-916, 2000.

P. H. Fischer, Traffic-related differences in outdoor and indoor concentrations of particles and volatile organic compounds in Amsterdam, Atmospheric Environment, vol.34, pp.3713-3722, 2000.

C. Minoia, Determination of environmental reference concentration of six PAHs in urban areas, Science of the Total Environment, vol.198, pp.33-41, 1997.

E. Menichini, Relationships between indoor and outdoor air pollution by carcinogenic PAHs and PCBs, Atmospheric Environment, vol.41, pp.9518-9529, 2007.

H. Choi, Estimating individual-level exposure to airborne polycyclic aromatic hydrocarbons throughout the gestational period based on personal, indoor, and outdoor monitoring, Environmental Health Perspectives, vol.116, pp.1509-1518, 2008.

T. Sugiyama, Size distribution of polycyclic aromatic hydrocarbons in indoor airborne particulates, Indoor and Built Environment, vol.9, pp.265-276, 2000.

C. Chao, Quantification of polycyclic aromatic hydrocarbons and aliphatic hydrocarbons in air particulate samples in homes, Indoor and Built Environment, vol.11, pp.123-133, 2002.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

I. Saito, Survey of indoor air chemicals (plasticizers, pesticides and bisphenol A), vol.54, pp.253-261, 2001.

T. Ohura, Characteristics of particle matter and associated polycyclic aromatic hydrocarbons in indoor and outdoor air in two cities in Shizuoka, Japan. Atmospheric Environment, vol.38, pp.2045-2054

K. Azuma, The risk screening for indoor air pollution chemicals in Japan, Risk Analysis, vol.27, pp.1623-1638, 2007.

C. A. Menzie, B. B. Potocki, and J. Santodonato, Exposure to carcinogenic PAHs in the environment, Environmental Science and Technology, vol.26, pp.1278-1284, 1992.

B. Brunekreef, Personal, indoor and outdoor exposures of PM 2.5 and its components for groups of cardiovascular patients in Amsterdam and Helsinki

M. A. Boston, , vol.127, 2005.

, Exposure factors handbook, 1997.

A. Thaqi, Biomarkers of exposure to passive smoking of school children: frequency and determinants, Indoor Air, vol.15, pp.302-310, 2005.

P. J. Lioy, The total human environmental exposure study (Thees) for benzo, Archives of Environmental Health, vol.43, pp.203-203, 1988.

, Polynuclear aromatic compounds. Part 1. Chemical, environmental and experimental data. Lyon, International Agency for Research Cancer, 1983 (IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans, vol.32

E. Manoli and C. Samara, Polycyclic aromatic hydrocarbons in natural water: sources, occurrence and analysis, Trends in Analytical Chemistry, vol.18, pp.417-428, 1999.

H. W. Chen, Distribution and risk assessment of polycyclic aromatic hydrocarbons in household drinking water, Bulletin of Environmental Contamination and Toxicology, vol.78, pp.201-205, 2007.

H. P. Nirmaier, Determination of polycyclic aromatic hydrocarbons in water samples using high-performance liquid chromatography with amperometric detection, Journal of Chromatography A, vol.730, pp.169-175, 1996.

D. Bodzek, Occurrence of PAHs in various elements of environment in Zabrze, Water, Air, and Soil Pollution, vol.103, pp.91-100, 1998.

P. J. Lioy and A. Greenberg, Factors associated with human exposures to polycyclic aromatic-hydrocarbons, Toxicology and Industrial Health, vol.6, pp.209-223, 1990.

B. K. Larsson, Polycyclic aromatic hydrocarbons in grilled food, Journal of Agricultural and Food Chemistry, vol.31, pp.867-873, 1983.

A. Ramesh, Bioavailability and risk assessment of orally ingested polycyclic aromatic hydrocarbons, International Journal of Toxicology, vol.23, pp.301-333, 2004.

R. Marti-cid, Evolution of the dietary exposure to polycyclic aromatic hydrocarbons in Catalonia, Spain. Food and Chemical Toxicology, vol.46, pp.3163-3173, 2008.

G. Falco, Polycyclic aromatic hydrocarbons in foods: human exposure through the diet in Catalonia, Spain. Journal of Food Protection, vol.66, pp.2325-2331, 2003.

L. R. Bordajandi, Survey of persistent organochlorine contaminants (PCBs, PCDD/Fs, and PAHs), heavy metals (Cu, Cd, Zn, Pb, and Hg), and arsenic in food samples from Huelva (Spain): levels and health implications, Journal of Agricultural and Food Chemistry, vol.52, pp.992-1001, 2004.

A. Douabul, Polynuclear aromatic hydrocarbons (PAHs) in fish from the Red Sea coast of Yemen, Hydrobiologia, vol.352, pp.251-262, 1997.

P. Jakszyn, Food content of potential carcinogenesis, 2004.

N. Kazerouni, Analysis of 200 food items for B[a]P and estimation of its intake in an epidemiologic study, Food and Chemical Toxicology, vol.39, pp.423-436, 2001.

B. M. Lee and G. A. Shim, Dietary exposure estimation of B[a]P and cancer risk assessment, Journal of Toxicology and Environmental Health, Part A, vol.70, pp.1391-1394, 2007.

R. H. De-vos, Polycyclic aromatic hydrocarbons in Dutch total diet samples (1984-1986), Food Chemistry and Toxicology, vol.28, pp.263-268, 1990.

R. Ibanez, Dietary intake of polycyclic aromatic hydrocarbons in a Spanish population, Journal of Food Protection, vol.68, pp.2190-2195, 2005.

K. E. Anderson, Dietary intake of heterocyclic amines and benzo[a] pyrene: associations with pancreatic cancer, Cancer Epidemiology Biomarkers & Prevention, vol.14, pp.2261-2265, 2005.

R. Hakami, Dietary intake of benzo[a]pyrene and risk of esophageal cancer in North of Iran, Nutrition and Cancer, vol.60, pp.216-221, 2008.

L. Turriobaldassarri, Polycyclic aromatic hydrocarbons in Italian national and regional diets, Polycyclic Aromatic Compounds, vol.10, pp.343-349, 1996.

A. Kulhanek, Crop-specific human exposure assessment for polycyclic aromatic hydrocarbons in Czech soils, Science of the Total Environment, vol.339, pp.71-80, 2005.

J. J. Nam, Distribution of polycyclic aromatic hydrocarbons in agricultural soils in South Korea, Chemosphere, vol.50, pp.1281-1289, 2003.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

D. Smith, Concentrations of particulate airborne polycyclic aromatic hydrocarbons and metals collected in Lahore, Pakistan. Atmospheric Environment, vol.30, pp.4031-4040, 1996.

M. Trapido, Polycyclic aromatic hydrocarbons in Estonian soil: contamination and profiles, Environmental Pollution, vol.105, pp.67-74, 1999.

H. W. Mielke, PAH and metal mixtures in New Orleans soils and sediments, Science of the Total Environment, vol.281, pp.217-227, 2001.

R. M. Harrison, Comparative receptor modelling study of airborne particulate pollutants in Birmingham (United Kingdom), Coimbra (Portugal) and Lahore (Pakistan), Atmospheric Environment, vol.31, pp.3309-3321, 1997.

W. Wilcke, Polycyclic aromatic hydrocarbons (PAHs) in soil -a review, Zeitschrift für Pflanzenernährung und Bodenkunde, vol.163, pp.229-248, 2000.

Z. Saltiene, D. Brukstiene, and A. Ruzgyte, Contamination of soil by polycyclic aromatic hydrocarbons in some urban areas, Polycyclic Aromatic Compounds, vol.22, pp.23-35, 2002.

E. Morillo, Soil pollution by PAHs in urban soils: a comparison of three European cities, Journal of Environmental Monitoring, vol.9, pp.1001-1008, 2007.

M. Nadal, M. Schuhmacher, and J. L. Domingo, Levels of PAHs in soil and vegetation samples from Tarragona County, Spain. Environmental Pollution, vol.132, pp.1-11, 2004.

S. R. Wild and K. C. Jones, Polynuclear aromatic hydrocarbons in the United Kingdom environment -a preliminary source inventory and budget, Environmental Pollution, vol.88, pp.91-108, 1995.

B. Maliszewska-kordybach, Polycyclic aromatic hydrocarbons in agricultural soils in Poland: preliminary proposals for criteria to evaluate the level of soil contamination, Applied Geochemistry, vol.11, pp.121-127, 1996.

L. L. Ma, Polycyclic aromatic hydrocarbons in the surface soils from outskirts of Beijing, China. Chemosphere, vol.58, pp.1355-1363, 2005.

J. Jeffries and I. Martin, Updated technical background to the CLEA model. Bristol, Environment Agency, 2008.

W. Wilcke, Polycyclic aromatic hydrocarbons in hydromorphic soils of the tropical metropolis Bangkok, Geoderma, vol.91, pp.297-309, 1999.

D. Wang, Seasonal variation of polycyclic aromatic hydrocarbon in soil and air of Dalian areas, China: an assessment of soil-air exchange, Journal of Environmental Monitoring, vol.10, pp.1076-1083, 2008.

L. C. Koo, Carcinogens in the indoor air of Hong-Kong homes -levels, sources, and ventilation effects on 7 polynuclear aromatic hydrocarbons, Environmental Technology, vol.15, pp.401-418, 1994.

R. M. Harrison, Measurement and modelling of exposure to selected air toxic concentrations for health effect studies and verification by biomarkers, 2009.

K. L. White, H. H. Lysy, and M. P. Holsapple, Immunosuppression by polycyclic aromatic hydrocarbons: a structure-activity relationship in B6C3F1 and DBA/2 mice, Immunopharmacology, vol.9, pp.155-164, 1985.

V. Anselstetter and H. Heimpel, Acute hematotoxicity of oral benzo[a]pyrene: the role of the Ah locus, Acta Haematologica, vol.76, pp.217-223, 1986.

N. Galván, Bone marrow cytotoxicity of benzo[a]pyrene is dependent on CYP1B1 but is diminished by Ah receptor-mediated induction of CYP1A1 in liver, Toxicology and Applied Pharmacology, vol.193, pp.84-96, 2003.

T. Shimada, Different mechanisms for inhibition of human cytochromes P450 1A1, 1A2, and 1B1 by polycyclic aromatic inhibitors, Chemical Research in Toxicology, vol.20, pp.489-496, 2007.

E. L. Cavalieri and E. G. Rogan, Central role of radical cations in metabolic activation of polycyclic hydrocarbons, Xenobiotica, vol.25, pp.677-688, 1995.

J. H. Park, Evidence for the aldo-keto reductase pathway of polycyclic aromatic trans-dihydrodiol activation in human lung A549 cells, Proceedings of the National Academy of Sciences, vol.105, pp.6846-6851, 2008.

P. Joseph and A. K. Jaiswal, NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo[a]pyrene quinones, British Journal of Cancer, vol.77, pp.709-719, 1998.

G. P. Casale, Detection and quantification of depurinated benzo[alpha] pyrene-adducted DNA bases in the urine of cigarette smokers and women exposed to household coal smoke, Chemical Research in Toxicology, vol.14, pp.192-201, 2001.

N. Balu, 8-quinone-3'-mononucleotide adduct standards for 32 P postlabeling analysis: detection of B[a]P-7,8-quinone-calf thymus DNA adducts, Analytical Biochemistry, vol.355, issue.7, pp.213-233, 2006.

D. S. Pushparajah, Up-regulation of the glutathione S-transferase system in human liver by polycyclic aromatic hydrocarbons; comparison with rat liver and lung, Mutagenesis, vol.23, pp.299-308, 2008.

S. Garte, Effects of metabolic genotypes on intermediary biomarkers in subjects exposed to PAHS: Results from the EXPAH study, Mutation Research, vol.620, pp.7-15, 2007.

J. A. Ross, Adenomas induced by polycyclic aromatic hydrocarbons in strain A/J mouse lung correlate with time-integrated DNA adduct levels, Cancer Research, vol.55, pp.1039-1044, 1995.

B. Binková, The effect of dibenzo[a,l]pyrene and B[a]P on human diploid lung fibroblasts: the induction of DNA adducts, expression of p53 and p21 WAF1 proteins and cell cycle distribution, Mutation Research, vol.471, pp.57-70, 2000.

Y. M. Shen, Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-B[a]P diol epoxide in vitro: role of reactive oxygen and biological selection, Chemical Research in Toxicology, vol.19, pp.1441-1450, 2006.

M. F. Denissenko, Preferential formation of B[a]P adducts at lung cancer mutational hotspots in P53, Science, vol.274, pp.430-432, 1996.

S. Wei, (a) pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in Chinese hamster V-79 cells, Cancer Research, vol.8, pp.3294-3301, 1993.

S. P. Hussain, Mutability of p53 hotspot codons to benzo[a]pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung, Cancer Research, vol.61, pp.6350-6355, 2001.

L. E. Smith, Targeting of lung cancer mutational hotspots by polycyclic aromatic hydrocarbons, Journal of the National Cancer Institute, vol.92, pp.803-811, 2000.

S. Park, B[a]P -induced DNA damage and p53 modulation in human hepatoma HepG2 cells for the identification of potential biomarkers for PAH monitoring and risk assessment, Toxicology Letters, vol.167, pp.27-33, 2006.

J. A. Ross and S. Nesnow, Polycyclic aromatic hydrocarbons: correlations between DNA adducts and ras oncogene mutations. Mutation Research/ Fundamental and Molecular Mechanisms of Mutagenesis, vol.424, pp.155-166, 1999.

D. M. Demarini, Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions, Cancer Research, vol.61, pp.6679-6681, 2001.

B. Mahadevan, Mutations induced by (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo[a,l]pyrene in the coding region of the hypoxanthine phosphoribosyltransferase (Hprt) gene in Chinese hamster V79 cells, Environmental and Molecular Mutagenesis, vol.41, pp.131-139, 2003.

O. Sevastyanova, Temporal variation in the genotoxic potential of urban air particulate matter, Mutation Research, vol.649, pp.179-186, 2008.

G. A. Umbuzeiro, Mutagenicity and DNA adduct formation of PAH, nitro-PAH and oxy-PAH fractions of atmospheric particulate matter from São Paulo, Brazil. Mutation Research, vol.652, pp.72-80, 2008.

B. Binková, In vitro genotoxicity of PAH mixtures and organic extract from urban air particles. Part I. Acellular assay, Mutation Research, vol.620, pp.114-122, 2007.

R. M. Maertens, J. Bailey, and P. A. White, The mutagenic hazards of settled house dust: a review, Mutation Research, vol.567, pp.401-425, 2004.

H. Xiao, 10-epoxide causes caspasemediated apoptosis in H460 human lung cancer cell line, Cell Cycle, vol.8, issue.9, pp.2826-2834, 2007.

J. H. Chen, Gaseous nitrogen oxide repressed benzo[a]pyrene-induced human lung fibroblast cell apoptosis via inhibiting JNK1 signals, Archives of Toxicology, vol.79, pp.694-704, 2005.

B. Mahadevan, Altered gene expression patterns in MCF-7 cells induced by the urban dust particulate complex mixture standard reference material 1649a, Cancer Research, vol.65, pp.1251-1258, 2005.

Y. C. Staal, Modulation of gene expression and DNA-adduct formation in precision-cut liver slices exposed to polycyclic aromatic hydrocarbons of different carcinogenic potency, Mutagenesis, vol.22, pp.55-62, 2007.

L. A. Hooven and W. M. Baird, Proteomic analysis of MCF-7 cells treated with B[a]P, dibenzo[a,l]pyrene, coal tar extract, and diesel exhaust extract, Toxicology, vol.249, pp.1-10, 2008.

H. Jyonouchi, Polycyclic aromatic hydrocarbon diol epoxides increase cytosolic Ca 2+ of airway epithelial cells, American Journal of Respiratory Cell and Molecular Biology, vol.25, pp.78-83, 2001.

, European Union Risk Assessment Report, Draft R323 0707, 2005.

J. Van-grevenynghe, Human CD34-positive hematopoietic stem cells constitute targets for carcinogenic polycyclic aromatic hydrocarbons, Journal of Pharmacology and Experimental Therapeutics, vol.314, pp.693-702, 2005.

B. Laupeze, Polycyclic aromatic hydrocarbons affect functional differentiation and maturation of human monocyte-derived dendritic cells, Journal of Immunology, vol.168, pp.2652-2658, 2002.

J. Van-grevenynghe, Cytochrome P450-dependent toxicity of environmental polycyclic aromatic hydrocarbons towards human macrophages, Biochemical and Biophysical Research Communications, vol.317, pp.708-716, 2004.

L. L. Allan, CYP1A1 in polycyclic aromatic hydrocarbon-induced B lymphocyte growth suppression, Biochemical and Biophysical Research Communications, vol.342, pp.227-235, 2006.

A. Penn and C. Snyder, Arteriosclerotic plaque development is 'promoted' by polynuclear aromatic hydrocarbons, Carcinogenesis, vol.9, pp.2185-2189, 1988.

K. Wakabayashi, Animal studies suggesting involvement of mutagen/ carcinogen exposure in atherosclerosis, Mutation Research, vol.239, pp.181-187, 1990.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

D. M. Curfs, Polycyclic aromatic hydrocarbons induce an inflammatory atherosclerotic plaque phenotype irrespective of their DNA binding properties, FASEB Journal, vol.19, pp.1290-1292, 2005.

A. M. Knaapen, The environmental carcinogen B[a]P induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis, Mutation Research, vol.621, pp.31-41, 2007.

K. M. Mackenzie and M. Angevine, Infertility in mice exposed in utero to benzo, Biology of Reproduction, vol.24, pp.183-191, 1981.

A. Ramesh, Alteration of fertility endpoints in adult male F-344 rats by subchronic exposure to inhaled benzo, Experimental and Toxicologic Pathology, vol.60, pp.269-280, 2008.

F. Inyang, Disruption of testicular steroidogenesis and epididymal function by inhaled benzo[a]pyrene, Reproductive Toxicology, vol.17, pp.527-537, 2003.

S. Shum, N. M. Jensen, and D. W. Nebert, The murine Ah locus: in utero toxicity and teratogenesis associated with genetic differences in B[a]P metabolism, Teratology, vol.20, pp.365-376, 1979.

A. E. Archibong, Alteration of pregnancy related hormones and fetal survival in F-344 rats exposed by inhalation to benzo[a]pyrene, Reproduction Toxicology, vol.16, pp.801-808, 2002.

J. Detmar, Fetal growth restriction triggered by polycyclic aromatic hydrocarbons is associated with altered placental vasculature and AhR-dependent changes in cell death, American Journal of Physiology, vol.295, pp.519-530, 2008.

M. K. Sanyal and Y. Li, Deleterious effects of polynuclear aromatic hydrocarbon on blood vascular system of the rat fetus, Birth Defects Research (Part B): Developmental and Reproductive Toxicology, vol.80, pp.367-373, 2007.

V. Kummer, Estrogenic activity of environmental polycyclic aromatic hydrocarbons in uterus of immature Wistar rats, Toxicology Letters, vol.180, pp.212-221, 2008.

G. D. Charles, Activity of B[a]P and its hydroxylated metabolites in an estrogen receptor-? reporter gene assay, Toxicological Sciences, vol.55, pp.320-326, 2000.

K. C. Fertuck, Interaction of PAH-related compounds with the ? and ? isoforms of the estrogen receptor, Toxicology Letters, vol.121, pp.167-177, 2001.

K. F. Arcaro, Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells, Toxicology, vol.133, pp.115-127, 1999.

Y. C. Staal, Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices, Mutagenesis, vol.23, pp.691-699, 2008.

Y. C. Staal, Binary PAH mixtures cause additive or antagonistic effects on gene expression but synergistic effects on DNA adduct formation, Carcinogenesis, vol.28, pp.2632-2640, 2007.

B. Mahadevan, Effect of a standardized complex mixture derived from coal tar on the metabolic activation of carcinogenic polycyclic aromatic hydrocarbons in human cells in culture, Chemical Research in Toxicology, vol.18, pp.224-231, 2005.

M. Huang, Inhibitory effect of 3-hydroxybenzo(a)pyrene on the mutagenicity and tumorigenicity of (±)7?,8?-dihydroxy-9?, Cancer Research, vol.8, pp.558-586, 1986.

N. C. Hughes and D. H. Phillips, Covalent binding of dibenzpyrenes and benzo[a] pyrene to DNA: evidence for synergistic and inhibitory interactions when applied in combination to mouse skin, Carcinogenesis, vol.11, pp.1611-1619, 1990.

L. A. Courter, Urban dust particulate matter alters PAH-induced carcinogenesis by inhibition of CYP1A1 and CYP1B1, Toxicological Sciences, vol.95, pp.63-73, 2007.

C. P. Marston, Effect of a complex environmental mixture from coal tar containing polycyclic aromatic hydrocarbons (PAH) on the tumor initiation, PAH-DNA binding and metabolic activation of carcinogenic PAH in mouse epidermis, Carcinogenesis, vol.22, pp.1077-1086, 2001.

S. Nesnow, Lung tumorigenic interactions in strain A/J mice of five environmental polycyclic aromatic hydrocarbons, vol.106, pp.1137-1346, 1998.

Z. Li, Concentration and profile of 22 urinary polycyclic aromatic hydrocarbon metabolites in the US population, Environmental Research, vol.107, pp.320-331, 2008.

E. Siwi?ska, The effect of coal stoves and environmental tobacco smoke on the level of urinary 1-hydroxypyrene, Mutation Research, vol.445, pp.147-163, 1999.

B. Chen, Higher urinary 1-hydroxypyrene concentration is associated with cooking practice in a Chinese population, Toxicology Letters, vol.171, pp.119-125, 2007.

G. Castaño-vinyals, Biomarkers of exposure to polycyclic aromatic hydrocarbons from environmental air pollution, Occupational and Environmental Medicine, vol.61, pp.1-9, 2004.

B. Pesch, Dose-response modeling of occupational exposure to polycyclic aromatic hydrocarbons with biomarkers of exposure and effect, Biomarkers & Prevention, vol.16, pp.1863-1873, 2007.

J. Topinka, Biomarkers of air pollution exposure -a study of policemen in Prague, Mutation Research, vol.624, pp.9-17, 2007.

F. P. Perera, Molecular and genetic damage in humans from environmental pollution in Poland, Nature, vol.360, pp.256-258, 1992.

H. Choi, International studies of prenatal exposure to polycyclic aromatic hydrocarbons and fetal growth, Environmental Health Perspectives, vol.114, pp.1744-1750, 2006.

S. V. Sizonenko, Impact of intrauterine growth restriction and glucocorticoids on brain development: insights using advanced magnetic resonance imaging, Molecular and Cellular Endocrinology, vol.254, pp.163-171, 2006.

A. Van-wassenaer, Neurodevelopmental consequences of being born SGA, Pediatric Endocrinology Reviews, vol.2, pp.372-377, 2005.

D. J. Barker, Fetal programming of coronary heart disease, Trends in Endocrinology and Metabolism, vol.13, pp.364-368, 2002.

Y. Xu, Hypoxia or nutrient restriction during pregnancy in rats leads to progressive cardiac remodeling and impairs postischemic recovery in adult male offspring, FASEB Journal, vol.20, pp.1251-1253, 2006.

R. L. Miller, Polycyclic aromatic hydrocarbons, environmental tobacco smoke, and respiratory symptoms in an inner-city birth cohort, Chest, vol.126, pp.1071-1078, 2004.

I. Hertz-picciotto, Early childhood lower respiratory illness and air pollution, Environmental Health Perspectives, vol.115, pp.1510-1518, 2007.

I. Burstyn, Polycyclic aromatic hydrocarbons and fatal ischemic heart disease, Epidemiology, vol.16, pp.744-750, 2005.
URL : https://hal.archives-ouvertes.fr/inserm-00266655

F. P. Perera, Effect of prenatal exposure to airborne polycyclic aromatic hydrocarbons on neurodevelopment in the first 3 years of life among innercity children, Environmental Health Perspectives, vol.114, pp.1287-1292, 2006.

D. Tang, Effects of prenatal exposure to coal-burning pollutants on children's development in China, Environmental Health Perspectives, vol.116, pp.674-679, 2008.

F. Perera, Benefits of reducing prenatal exposure to coal-burning pollutants to children's neurodevelopment in China, Environmental Health Perspectives, vol.116, pp.1396-1400, 2008.

V. K. Singh, Blood levels of polycyclic aromatic hydrocarbons in children and their association with oxidative stress indices: an Indian perspective, Clinical Biochemistry, vol.41, pp.152-161, 2008.

M. Ruchirawat, Assessment of potential cancer risk in children exposed to urban air pollution in, Toxicology Letters, vol.168, pp.200-209, 2007.

J. Topinka, Biomarkers of air pollution exposure -a study of policemen in Prague. Mutation Research -Fundamental and Molecular Mechanisms of Mutagenesis, vol.624, pp.9-17, 2007.

R. J. Sram, Environmental exposure to carcinogenic polycyclic aromatic hydrocarbons. The interpretation of cytogenetic analysis by FISH, Toxicology Letters, vol.172, pp.12-20, 2007.

R. J. Sram, Chromosomal aberrations in environmentally exposed population in relation to metabolic and DNA repair genes polymorphisms. Mutation Research -Fundamental and Molecular Mechanisms of Mutagenesis, vol.620, pp.22-33, 2007.

A. Rossnarova, The impact of air pollution on the levels of micronuclei measured by automated image analysis. Mutation Research -Fundamental and Molecular Mechanisms of Mutagenesis, vol.669, pp.42-47, 2009.

J. Rubes, Genetic polymorphisms influence the susceptibility of men to sperm DNA damage associated with exposure to air pollution. Mutation Research -Fundamental and Molecular Mechanisms of Mutagenesis, vol.683, pp.9-15, 2010.

K. Straif, Carcinogenicity of household solid fuel combustion and of high-temperature frying, Lancet Oncology, vol.7, pp.977-978, 2006.

, Smokeless tobacco and some tobacco-specific N-nitrosamines. Lyon, International Agency for Research on Cancer, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol.89, 2004.

M. D. Gammon, Polycyclic aromatic hydrocarbon-DNA adducts and breast cancer: a pooled analysis, Archives of Environmental Health, vol.59, pp.640-649, 2004.

M. Peluso, DNA adducts and lung cancer risk: a prospective study, Cancer Research, vol.65, pp.8042-8048, 2005.

M. J. Gunter, Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study, Carcinogenesis, vol.26, pp.637-642, 2005.

K. D. Crew, Genetic polymorphisms in the apoptosis-associated genes FAS and FASL and breast cancer risk, Carcinogenesis, vol.28, pp.2548-2551, 2007.

K. M. Mccarty, PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer risk, vol.117, pp.552-558, 2009.

D. Li, Aromatic DNA adducts in adjacent tissues of breast cancer patients: clues to breast cancer etiology, Cancer Research, vol.56, pp.287-293, 1996.

A. Rundle, The relationship between genetic damage from polycyclic aromatic hydrocarbons in breast tissue and breast cancer, Carcinogenesis, vol.21, pp.1281-1289, 2000.

S. K. Sagiv, Polycyclic aromatic hydrocarbon-DNA adducts and survival among women with breast cancer, Environmental Research, vol.109, pp.287-291, 2009.

B. A. Rybicki, Polycyclic aromatic hydrocarbon-DNA adducts in prostate and biochemical recurrence after prostatectomy, Clinical Cancer Research, vol.14, pp.750-757, 2008.

B. Armstrong, Lung cancer risk after exposure to polycyclic aromatic hydrocarbons: a review and meta-analysis, vol.112, pp.970-978, 2004.

B. G. Armstrong and G. Gibbs, Exposure-response relationship between lung cancer and polycyclic aromatic hydrocarbons (PAHs): estimates from a large aluminium smelter cohort, Occupational and Environmental Medicine, vol.66, pp.740-746, 2009.

C. Bosetti, P. Boffetta, L. Vecchia, and C. , Occupational exposures to polycyclic aromatic hydrocarbons, and respiratory and urinary tract cancers: a quantitative review to, Annals of Oncology, vol.18, pp.431-446, 2005.

, Some non-heterocyclic polycyclic aromatic hydrocarbons and some related exposures. Lyon, International Agency for Research on Cancer, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol.92, 2006.

, United Nations Scientific Committee on the Effects of Atomic Radiation. Sources and effects of ionizing radiation. Report to the General Assembly, 2000.

F. Bochicchio, J. P. Mclaughlin, and S. Piermattel, Radon in indoor air, European Collaborative Action -Indoor Air Quality and its Impact on Man, 1995.

, International Commission on Radiological Protection, vol.65, 1994.

, WHO handbook on indoor radon : a public health perspective. Geneva, World Health Organization, 2009.

N. Hunter, Year-to-year variations in radon levels in a sample of UK houses with the same occupants, The natural radiation environment VII. Seventh International Symposium on the Natural Radiation Environment, pp.438-447, 2002.

S. A. Durrani, Radon measurements by etched track detectors: applications in radiation protection, earth sciences and the environment, 1997.

J. Miles and J. Sinnaeve, The value of intercomparisons in radon metrology, Radiation Protection Dosimetry, vol.24, pp.313-316, 1988.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

A. C. George, State of the art instruments for measuring radon/thoron and progeny in dwellings -a review, Health Physics, vol.70, pp.451-463, 1996.

P. Kotrappa, A practical electret passive environmental radon monitor system for indoor radon measurement, Health Physics, vol.58, pp.461-467, 1990.

J. P. Mclaughlin, Approaches to the assessment of long term exposure to radon and its progeny, Science of the Total Environment, vol.272, pp.53-60, 2001.

C. Walsh and J. P. Mclaughlin, Correlation of 210 Po implanted in glass with radon gas exposure: sensitivity analysis of critical parameters using a Monte-Carlo approach, Science of the Total Environment, vol.272, pp.195-202, 2001.

A. Dantas, In vivo measurements of 210 Pb in skull and knee geometries as an indicator of cumulative 222 Rn exposure in an underground coal mine in Brazil, Radiation Protection Dosimetry, vol.127, pp.325-328, 2007.

I. Makelainen, Correlations between radon concentration and indoor gamma dose rate, soil permeability and dwelling substructure and ventilation, Science of the Total Environment, vol.272, pp.283-289, 2001.

G. Keller, Radon permeability and radon exhalation of building materials, Science of the Total Environment, vol.272, pp.85-89, 2001.

, Health risks of radon and other internally deposited alpha-emitters, 1988.

G. M. Kendall and T. J. Smith, Doses to organs and tissues from radon and its decay products, Journal of Radiological Protection, vol.22, pp.389-406, 2002.

G. Dubois, An overview of radon surveys in Europe, European Commission, 2005.

S. Tokonami, Radon and thoron exposures for cave residents in Shanxi and Shaanxi Provinces, Radiation Research, vol.162, pp.396-406, 2004.

T. Ishikawa, Calculation of dose conversion factors for thoron decay products, Journal of Radiological Protection, vol.27, pp.447-456, 2007.

A. Chevillard, Transport of 222 Rn using the regional model REMO: a detailed comparison with measurements over, Europe. Tellus, vol.54, pp.850-871, 2002.

, United Nations Scientific Committee on the Effects of Atomic Radiation. Sources-to-effects assessment for radon in homes and workplaces. Report to the General Assembly, United Nations, 2008.

J. Porstendörfer, International Commission on Radiological Protection. Human respiratory tract model for radiological protection, Journal of Aerosol Science, vol.25, pp.1-3, 1994.

R. Winkler-heil, Comparison of radon lung dosimetry models for the estimation of dose uncertainties. Radiation Protection Dosimetry, vol.127, pp.27-30, 2007.

J. W. Marsh, Dosimetric models used in the alpha-risk project to quantify exposure of uranium miners to radon gas and its progeny, Radiation Protection Dosimetry, vol.130, pp.101-106, 2008.

G. M. Kendall and T. J. Smith, Doses from radon and its decay products to children, Journal of Radiological Protection, vol.25, pp.241-256, 2005.

F. T. Cross and G. Monchaux, Risk assessment of radon health effects from experimental studies. A joint review of PNNL (USA) and CEA-COGEMA (France) data, 1999.

, Committee on the Biological Effects of Ionizing Radiation (BEIR VI). Health effects of exposure to radon -BEIR VI, 1999.

J. P. Morlier, Lung cancer incidence after exposure of rats to low doses of radon: influence of dose-rate, Radiation Protection Dosimetry, vol.56, pp.93-97, 1994.

G. Monchaux, Carcinogenic and co-carcinogenic effects of radon and radon daughters in rats, vol.102, pp.64-73, 1994.

G. Monchaux and J. P. Morlier, Influence of exposure rate on radon-induced lung cancer in rats, Journal of Radiological Protection, vol.22, pp.81-87, 2002.

M. Tirmarche, Quantification of lung cancer risk after low radon exposure and low exposure rate: synthesis from epidemiological and experimental data, 2003.

C. G. Collier, Carcinogenicity of radon/radon decay product inhalation in rats -effect of dose, dose rate and unattached fraction, International Journal of Radiation Biology, vol.81, pp.631-647, 2005.

B. Grosche, Lung cancer risk among German male uranium miners: a cohort study, British Journal of Cancer, vol.95, pp.1280-1287, 1946.

L. Tomasek, Lung cancer in French and Czech uranium miners: radonassociated risk at low exposure rates and modifying effects of time since exposure and age at exposure, Radiation Research, vol.169, pp.125-137, 2008.

L. Walsh, The influence of radon exposures on lung cancer mortality in German uranium miners, Radiation Research, vol.173, pp.79-90, 1946.

H. Bijwaard, M. J. Brugmans, and H. Leenhouts, A consistent two-mutation model of lung cancer for different data sets of radon-exposed rats, Radiation and Environmental Biophysics, vol.40, pp.269-277, 2001.

W. F. Heidenreich, Two-step model for the risk of fatal and incidental lung tumors in rats exposed to radon, Radiation Research, vol.151, pp.209-219, 1999.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

J. C. Kaiser, Lung tumour risk in radon-exposed rats from different experiments: comparative analysis with a biologically based models, Radiation and Environmental Biophysics, vol.43, pp.189-201, 2004.

W. Hofmann, Modelling lung cancer incidence in rats following exposure to radon progeny, Radiation Protection Dosimetry, vol.122, pp.345-348, 2006.

R. F. Jostes, Genetic, cytogenetic and carcinogenic effects of radon: a review, Mutation Research, vol.340, pp.125-139, 1996.

D. J. Brenner, J. B. Little, and K. Saks, The bystander effect in radiation onocogenesis: II. A quantitative model, Radiation Research, vol.155, pp.402-408, 2001.

D. J. Brenner and R. K. Sachs, Do low dose-rate bystander effects influence domestic radon risks?, International Journal of Radiation Biology, vol.78, pp.593-604, 2002.

D. J. Brenner and R. K. Sachs, Domestic radon risks may be dominated by bystander effects -but the risks are unlikely to be greater than we thought, Health Physics, vol.85, pp.103-108, 2003.

M. P. Little, The bystander effect model of Brenner and Sachs fitted to lung cancer data in 11 cohorts of underground miners, and equivalence of fit of a linear relative risk model with adjustment for attained age and age at exposure, Journal of Radiological Protection, vol.24, pp.243-255, 2004.

, Man-made mineral fibres and radon. Lyon, International Agency for Research on Cancer, IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol.43, 1988.

B. Langholz, Latency analysis in epidemiologic studies of occupational exposures: application to the Colorado Plateau uranium miners cohort, American Journal of Industrial Medicine, vol.35, pp.246-256, 1999.

D. O. Stram, Correcting for exposure measurement error in a reanalysis of lung cancer mortality for the Colorado Plateau Uranium Miners cohort. Health Physics, vol.77, pp.265-275, 1999.

M. Hauptmann, Using splines to analyse latency in the Colorado Plateau uranium miners cohort, Journal of Epidemiology and Biostatistics, vol.6, pp.417-424, 2001.

R. W. Hornung, Health effects in underground uranium miners, Occupational Medicine, vol.16, pp.331-344, 2001.

V. E. Archer, Latency and the lung cancer epidemic among United States uranium miners, Health Physics, vol.87, pp.480-489, 2004.

W. D. Hazelton, Analysis of a historical cohort of Chinese tin miners with arsenic, radon, cigarette smoke, and pipe smoke exposures using the biologically based two-stage clonal expansion model, Radiation Research, vol.156, pp.78-94, 2001.

W. F. Heidenreich, Studies of radon-exposed miner cohorts using a biologically based model: comparison of current Czech and French data with historic data from China and Colorado, Radiation and Environmental Biophysics, vol.43, pp.247-256, 2004.

M. J. Brugmans, Radon-induced lung cancer in French and Czech miner cohorts described with a two-mutation model, Radiation and Environmental Biophysics, vol.43, pp.153-163, 2004.

L. Tomasek, Czech miner studies of lung cancer risk from radon, Journal of Radiological Protection, vol.22, pp.107-112, 2002.

L. Tomasek and H. Zarska, Lung cancer risk among Czech tin and uranium miners -comparison of lifetime detriment, Neoplasma, vol.51, pp.255-260, 2004.

A. Rogel, Lung cancer risk in the French cohort of uranium miners, Journal of Radiological Protection, vol.22, pp.101-106, 2002.

D. Laurier, An update of cancer mortality among the French cohort of uranium miners: extended follow-up and new source of data for causes of death, European Journal of Epidemiology, vol.19, pp.139-146, 2004.

B. Vacquier, Mortality risk in the French cohort of uranium miners: extended follow-up 1946-1999, Occupational and Environmental Medicine, vol.65, pp.597-604, 2008.

B. Vacquier, Radon-associated lung cancer risk among French uranium miners: modifying factors of the exposure-risk relationship, Radiation and Environmental Biophysics, vol.48, pp.1-9, 2009.

P. J. Villeneuve, H. Morrison, and R. Lane, Radon and lung cancer risk: an extension of the mortality follow-up of the Newfoundland fluorspar cohort. Health Physics, vol.92, pp.157-169, 2007.

L. H. Veiga, Feasibility study for a long-term follow-up in a historical cohort of Brazilian coal miners, Journal of Radiological Protection, vol.27, pp.349-360, 2007.

M. Kreuzer, Characteristics of the German uranium miners cohort study, Health Physics, vol.83, pp.26-34, 2002.

M. Kreuzer, Radon and risk of death from cancer and cardiovascular diseases in the German uranium miners cohort study: follow-up, Radiation and Environmental Biophysics, vol.49, pp.177-185, 1946.

J. Skowronek and B. Zemla, Epidemiology of lung and larynx cancers in coal mines in Upper Silesia -preliminary results, Health Physics, vol.85, pp.365-370, 2003.

I. Brueske-hohlfeld, Lung cancer risk among former uranium miners of the Wismut company in Germany, Health Physics, vol.90, pp.208-216, 2006.

J. S. Puskin, Smoking as a confounder in ecologic correlations of cancer mortality rates with average county radon levels, Health Physics, vol.84, pp.526-532, 2003.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

J. H. Lubin, J. D. Boice, and J. , Lung cancer risk from residential radon: metaanalysis of eight epidemiologic studies, Journal of the National Cancer Institute, vol.89, pp.49-57, 1997.

J. H. Lubin, Indoor radon and the risk of lung cancer, Proceedings of the American Statistical Association Conference on Radiation and Health Radiation Research, vol.151, pp.105-107, 1999.

M. Pavia, Meta-analysis of residential exposure to radon gas and lung cancer, Bulletin of the World Health Organization, vol.81, pp.732-738, 2003.

S. Darby, Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies, British Medical Journal, vol.330, pp.223-227, 2005.

S. Darby, Residential radon and lung cancer: detailed results of a collaborative analysis of individual data on 7,148 subjects with lung cancer and 14,208 subjects without lung cancer from 13 epidemiological studies in Europe, Scandinavian Journal of Work, vol.32, pp.1-83, 2006.

D. Krewski, Residential radon and risk of lung cancer: a combined analysis of 7 North American case-control studies, Epidemiology, vol.16, pp.137-145, 2005.

D. Krewski, A combined analysis of North American case-control studies of residential radon and lung cancer, Journal of Toxicology and Environmental Health A, vol.69, pp.533-597, 2006.

J. H. Lubin, Risk of lung cancer and residential radon in China: pooled results of two studies, International Journal of Cancer, vol.109, pp.132-137, 2004.

J. H. Lubin, Estimating lung cancer mortality from residential radon using data for low exposures of miners, Radiation Research, vol.147, pp.126-134, 1997.

D. Laurier, M. Valenty, and M. Tirmarche, Radon exposure and the risk of leukemia: a review of epidemiological studies, Health Physics, vol.81, pp.272-288, 2001.

V. Rericha, Incidence of leukemia, lymphoma, and multiple myeloma in Czech uranium miners: a case-cohort study, Environmental Health Perspectives, vol.114, pp.818-822, 2006.

O. Raaschou-nielsen, Domestic radon and childhood cancer in Denmark, Epidemiology, vol.19, pp.536-543, 2008.

A. S. Evrard, Childhood leukemia incidence and exposure to indoor radon, terrestrial and cosmic gamma radiation, Health Physics, vol.90, pp.569-579, 2006.
URL : https://hal.archives-ouvertes.fr/inserm-00137972

M. Mohner, Leukemia and exposure to ionizing radiation among German uranium miners, American Journal of Industrial Medicine, vol.49, pp.238-248, 2006.

M. Kreuzer, Radon and risk of extrapulmonary cancers -results of the German uranium miners cohort study, British Journal of Cancer, vol.99, pp.1946-1953, 1960.

L. Tomasek, Radon exposure and cancer other than lung cancer among uranium miners in West Bohemia, Lancet, vol.34, pp.919-923, 1993.

B. Vacquier, Mortality risk in the French cohort of uranium miners: extended follow-up 1946-1999, Occupational and Environmental Medicine, vol.65, pp.597-604, 2008.

S. Darby, Radon and cancers other than lung cancer in underground miners: a collaborative analysis of 11 studies, Journal of the National Cancer Institute, vol.87, pp.378-384, 1995.

M. Mohner, Ionizing radiation and risk of laryngeal cancer among German uranium miners, Health Physics, vol.95, pp.725-733, 2008.

P. J. Villeneuve and H. I. Morrison, Coronary heart disease mortality among Newfoundland fluorspar miners, Scandinavian Journal of Work, vol.23, pp.221-226, 1997.

P. J. Villeneuve, R. Lane, and H. I. Morrison, Coronary heart disease mortality and radon exposure in the Newfoundland fluorspar miners' cohort, Radiation and Environmental Biophysics, vol.46, pp.291-296, 1950.

M. Kreuzer, Mortality from cardiovascular diseases in the German uranium miners cohort study, Radiation and Environmental Biophysics, vol.45, pp.159-166, 2006.

X. Z. Xuan, A cohort study in southern China of tin miners exposed to radon and radon decay products, Health Physics, vol.64, pp.123-131, 1993.

L. Tomasek, Mortality in uranium miners in west Bohemia: a long term cohort study, Occupational and Environmental Medicine, vol.51, pp.308-315, 1994.

B. Bolviken, Radon: a possible risk factor in multiple sclerosis, Neuroepidemiology, vol.22, pp.87-94, 2003.

, International radon project survey on radon guidelines, programmes and activities. Geneva, World Health Organization, 2007.

, European Union risk assessment report, Trichloroethylene. Brussels, 2004.

, Agency for Toxic Substances and Disease Registry (ATSDR), 1997.

, Dry cleaning, some chlorinated solvents and other industrial chemicals. Summary of data reported and evaluation. Lyon, International Agency for Research on Cancer, Evaluation of Carcinogenic Risks to Humans, vol.63, 1995.

. Trichloroethylene and . Geneva, World Health Organization, 1985.

. Trichloroethylene, Priority substances assessment report for the Canadian Environmental Protection Act. Ottawa, Environment Canada and Health Canada, 1993.

, German Chemical Society. Trichloroethene. Stuttgart, Hirzel, 1994.

R. G. Lewis and S. M. Gordon, Sampling for organic chemicals in air, Principles of environmental sampling, pp.401-470, 1996.

, Draft guidance for evaluating the vapor intrusion to indoor air pathway from groundwater and soils (subsurface vapor intrusion guidance), 2002.

S. Haddad, G. C. Tardif, and R. Tardif, Development of physiologically based toxicokinetic models for improving the human indoor exposure assessment to water contaminants: trichloroethylene and trihalomethanes, Journal of Toxicology and Environmental Health, Part A, vol.69, pp.2095-2136, 2006.

C. Fan, Risk assessment of exposure to volatile organic compounds in groundwater in Taiwan, Science of the Total Environment, vol.407, pp.2165-2174, 2009.

, Sources, emission, and exposure for trichloroethylene (TCE) and related compounds, 2001.

J. L. Adgate, Outdoor, indoor, and personal exposure to VOCs in children, vol.112, pp.1386-1392, 2004.

J. L. Adgate, Personal, indoor, and outdoor VOC exposures in a probability sample of children, Journal of Exposure Analysis and Environmental Epidemiology, vol.14, pp.4-13, 2004.

C. A. Clayton, National Human Exposure Assessment Survey (NHEXAS): distributions and associations of lead, arsenic and volatile organic compounds in EPA Region 5, Journal of Exposure Analysis and Environmental Epidemiology, vol.9, pp.381-392, 1999.

D. C. Payne-sturges, Personal exposure meets risk assessment: a comparison of measured and modeled exposures and risks in an urban community, Environmental Health Perspectives, vol.112, pp.589-598, 2004.

S. N. Sax, Differences in source emission rates of volatile organic compounds in inner-city residences of, Journal of Exposure Analysis and Environmental Epidemiology, vol.14, pp.95-109, 2004.

K. Sexton, Comparison of personal, indoor, and outdoor exposures to hazardous air pollutants in three urban communities, Environmental Science and Technology, vol.38, pp.423-430, 2004.

M. R. Van-winkle and P. A. Scheff, Volatile organic compounds, polycyclic aromatic hydrocarbons and elements in the air of ten urban homes, Indoor Air, vol.11, pp.49-64, 2001.

C. P. Weisel, Relationship between indoor, outdoor and personal air (RIOPA). Houston, TX, Health Effects Institute and National Urban Air Toxics Research Center, 2005.

M. J. Jantunen, Air pollution exposure in European cities: the EXPOLIS Study. Kuopio, National Public Health Institute, 1999.

S. Kirchner, National dwellings survey: report on air quality in French dwellings, Final Report, Indoor Air Quality Observatory, 2006.

T. Ohura, Organic air pollutants inside and outside residences in Shimizu, Japan: levels, sources and risks, Science of the Total Environment, vol.366, pp.485-499, 2006.

, Building Assessment Survey and Evaluation (BASE) Study, 2008.

C. Y. Chao and G. Y. Chan, Quantification of indoor VOCs in twenty mechanically ventilated buildings in Hong Kong, Atmospheric Environment, vol.35, pp.5895-5913, 2001.

B. M. Eklund, Spatial and temporal variability in VOC levels within a commercial retail building, Indoor Air, vol.18, pp.365-374, 2008.

H. Guo, Risk assessment of exposure to volatile organic compounds in different indoor environments, Environmental Research, vol.94, pp.57-66, 2004.

M. M. Loh, Measured concentrations of VOCs in several non-residential microenvironments in the United States, Environmental Science & Technology, vol.40, pp.6903-6911, 2006.

V. Grote and J. , Reduction of occupational exposure to perchloroethylene and trichloroethylene in metal degreasing over the last 30 years: influences of technology innovation and legislation, Journal of Exposure Analysis and Environmental Epidemiology, vol.13, pp.325-340, 2003.

X. I. You, Determinants of airborne concentrations of volatile organic compounds in rural areas of Western Canada, Journal of Exposure Science and Environmental Epidemiology, vol.18, pp.117-128, 2008.

C. Y. Chan, Volatile organic compounds in roadside microenvironments of metropolitan Hong Kong, Atmospheric Environment, vol.36, pp.2039-2047, 2002.

L. H. Lash, Metabolism of trichloroethylene, Environmental Health Perspectives, vol.108, pp.177-200, 2000.

W. A. Chiu, Issues in the pharmacokinetics of trichloroethylene and its metabolites, Environmental Health Perspectives, vol.114, pp.1450-1456, 2006.

, Guidelines for Canadian drinking water quality: supporting documentation, 2005.

. Trichloroethylene and . Geneva, International Programme on Chemical Safety, issue.50, 1985.

, Fiches de données toxicologiques et environnementales des substances chimiques: trichloroéthylène. Verneuil-en-Halatte, Institut National de l'Environnement Industriel et des Risques, 2005.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

, Hazardous Substances Data Bank (HSDB) [online database

M. D. Bethesda, , p.19, 2010.

. Trichloroethylene, Air quality guidelines for Europe, 2000.

J. C. Caldwell and N. Keshava, Key issues in the modes of action and effects of trichloroethylene metabolites for liver and kidney tumorigenesis, Environmental Health Perspectives, vol.114, pp.1457-1463, 2006.

D. H. Ramdhan, Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1, Toxicology and Applied Pharmacology, vol.231, pp.300-307, 2008.

S. Kim, Pharmacokinetic analysis of trichloroethylene metabolism in male B6C3F1 mice: formation and disposition of trichloroacetic acid, dichloroacetic acid, S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, Toxicology and Applied Pharmacology, vol.238, pp.90-99, 2009.

J. C. Lipscomb, In vitro to in vivo extrapolation for trichloroethylene metabolism in humans, Toxicology and Applied Pharmacology, vol.152, pp.376-387, 1998.

, Indoor air quality guidelines for trichloroethylene, 2009.

A. R. Goeptar, Metabolism and kinetics of trichloroethlyene in relation to toxicity and carcinogenicity. Relevance of the mercapturic pathway, Chemical Research in Toxicology, vol.8, pp.3-21, 1995.

J. L. Merdink, Kinetics of chloral hydrate and its metabolites in male human volunteers, Toxicology, vol.245, pp.130-140, 2008.

, TLVs and BEIs based on the documentation of the threshold limit values for chemical substances and physical agents and biological exposure indices, 2006.

J. C. Waksman and S. D. Phillips, Biologic markers of exposure to chlorinated solvents, Clinics in Occupational and Environmental Medicine, vol.4, pp.413-421, 2004.

M. D. Sohn, T. E. Mckone, and J. N. Blancato, Reconstructing population exposures from dose biomarkers: inhalation of trichloroethylene (TCE) as a case study, Journal of Exposure Analysis and Environmental Epidemiology, vol.14, pp.204-213, 2004.

K. H. Liao, Y. M. Tan, and H. J. Clewell, Development of a screening approach to interpret human biomonitoring data on volatile organic compounds: reverse dosimetry on biomonitoring data for trichloroethylene, Risk Analysis, vol.27, pp.1223-1236, 2007.

B. C. Allen and J. W. Fisher, Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans, Risk Analysis, vol.13, pp.71-86, 1993.

R. Abbas and J. W. Fisher, A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice, Toxicology and Applied Pharmacology, vol.147, pp.15-30, 1997.

J. W. Fisher, D. Mahle, and R. Abbas, A human physiologically based pharmacokinetic model for trichloroethylene and its metabolites, trichloroacetic acid and free trichloroethanol, Toxicology and Applied Pharmacology, vol.152, pp.339-359, 1998.

J. W. Fisher, Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites, Environmental Health Perspectives, vol.108, pp.265-273, 2000.

M. S. Greenberg, G. A. Burton, and J. W. Fisher, Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice, Toxicology and Applied Pharmacology, vol.154, pp.264-278, 1999.

. Clewell, Development of a physiologically based pharmacokinetic model of trichloroethylene and its metabolites for use in risk assessment, Environmental Health Perspectives, vol.108, pp.283-305, 2000.

F. Y. Bois, Statistical analysis of Fisher et al. PBPK model of trichloroethylene kinetics, Environmental Health Perspectives, vol.108, pp.275-282, 2000.
URL : https://hal.archives-ouvertes.fr/ineris-00961853

F. Y. Bois, Statistical analysis of Clewell et al. PBPK model of trichloroethylene kinetics, Environmental Health Perspectives, vol.108, pp.307-316, 2000.
URL : https://hal.archives-ouvertes.fr/ineris-00961854

W. A. Chiu, M. S. Okino, and M. V. Evans, Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK model, and Bayesian approach, Toxicology and Applied Pharmacology, vol.241, pp.36-60, 2009.

, Report of the peer consultation of harmonized PBPK model for trichloroethylene, Toxicology Excellence for Risk Assessment, 2004.

M. Yoon, M. C. Madden, and H. A. Barton, Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose metrics, Journal of Toxicology and Environmental Health, Part A, vol.70, pp.1527-1541, 2007.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

J. E. Simmons, A physiologically based pharmacokinetic model for trichloroethylene in the male long-evans rat, Toxicological Sciences, vol.69, pp.3-15, 2002.

J. V. Bruckner, D. A. Keys, and J. W. Fisher, The Acute Exposure Guideline Level (AEGL) program: applications of physiologically based pharmacokinetic modeling, Journal of Toxicology and Environmental Health, Part A, vol.67, pp.621-634, 2004.

W. K. Boyes, Duration adjustment of acute exposure guideline level values for trichloroethylene using a physiologically-based pharmacokinetic model, Risk Analysis, vol.25, pp.677-686, 2005.

J. E. Simmons, M. V. Evans, and W. K. Boyes, Moving from external exposure concentration to internal dose: duration extrapolation based on physiologically based pharmacokinetic derived estimates of internal dose, Journal of Toxicology and Environmental Health, Part A, vol.68, pp.927-950, 2005.

C. E. Hacks, Bayesian population analysis of a harmonized physiologically bases pharmacokinetic model of trichloroethylene and its metabolites, Regulatory Toxicology and Pharmacology, vol.46, pp.63-83, 2006.

M. V. Evans, Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in induced hepatomegaly, Toxicology and Applied Pharmacology, vol.236, pp.329-340, 2009.

B. M. Kulig, The effects of chronic trichloroethylene exposure on neurobehavioral functioning in the rat, Neurotoxicology and Teratology, vol.9, pp.171-178, 1987.

C. S. Rebert, Sensory-evoked potentials in rats chronically exposed to trichloroethylene: predominant auditory dysfunction, Neurotoxicology and Teratology, vol.13, pp.83-90, 1991.

H. Arito, M. Takahashi, and T. Ishikawa, Effect of subchronic inhalation exposure to low-level trichloroethylene on heart rate and wakefulness-sleep in freely moving rats, Sangyo Igaku, vol.36, pp.1-8, 1994.

L. Blain, P. Lachapelle, and S. Molotchnikoff, Electroretinal responses are modified by chronic exposure to trichloroethylene, Neurotoxicology, vol.15, pp.627-631, 1994.

A. Vyskocil, Ototoxicity of trichloroethylene in concentrations relevant for the working environment, Human and Experimental Toxicology, vol.27, pp.195-200, 2008.

D. M. Gash, Trichloroethylene: parkinsonism and complex 1 mitochondrial neurotoxicity, Annals of Neurology, vol.63, pp.184-192, 2008.

Y. Sano, Trichloroethylene liver toxicity in mouse and rat: microarray analysis reveals species differences in gene expression, Archives of Toxicology, vol.83, pp.835-849, 2009.

J. A. Prendergast, Effects on experimental animals of long-term inhalation of trichloroethylene, carbon tetrachloride, 1,1,1-trichloroethane, dichlorodifluoromethane, and 1,1-dichloroethylene, Toxicology and Applied Pharmacology, vol.10, pp.270-289, 1967.

C. Maltoni, Long-term carcinogenicity bioassays on trichloroethylene administered by inhalation to Sprague-Dawley rats and Swiss mice and B3C6F1 mice, Annals of the New York Academy of Sciences, vol.534, pp.316-342, 1988.

L. H. Lash, Modulation of hepatic and renal metabolism and toxicity of trichloroethylene and perchloroethylene by alterations in status of cytochrome P450 and glutathione, Toxicology, vol.235, pp.11-26, 2007.

S. Khan, Effect of trichloroethylene (TCE) toxicity on the enzyme carbohydrate metabolism, brush border membrane and oxidative stress in kidney and other rat tissues, Food and Chemical Toxicology, vol.47, pp.1562-1568, 2009.

X. Y. Chen, Immune responses to trichloroethylene and skin gene expression profiles in Sprague Dawley rats, Biomedical and Environmental Sciences, vol.19, pp.346-352, 2006.

M. Seo, Augmentation of antigen-stimulated allergic responses by a small amount of trichloroethylene ingestion from drinking water, Regulatory Toxicology and Pharmacology, vol.52, pp.140-146, 2008.

P. Cai, Chronic exposure to trichloroethene causes early onset of SLElike disease in female MRL +/+ mice, Toxicology and Applied Pharmacology, vol.228, pp.68-75, 2008.

P. Cai, Immuno-and hepato-toxicity of dichloroacetic acid in MRL +/+ and B6C3F1 mice, Journal of Immunotoxicology, vol.4, pp.107-115, 2007.

P. Cai, Differential immune responses to albumin adducts of reactive intermediates of trichloroethene in MRL+/+ mice, Toxicology and Applied Pharmacology, vol.220, pp.278-283, 2007.

X. Tang, Characterization of liver injury associated with hypersensitive skin reactions induced by trichloroethylene in the guinea pig maximization test, Journal of Occupational Health, vol.50, pp.114-121, 2008.

K. M. Gilbert, Delineating liver events in trichloroethylene-induced autoimmune hepatitis, Chemical Research in Toxicology, vol.22, pp.626-632, 2009.

G. Wang, Increased nitration and carbonylation of proteins in MRL+/+ mice exposed to trichloroethene: potential role of protein oxidation in autoimmunity, Toxicology and Applied Pharmacology, vol.237, pp.188-195, 2009.

T. Shen, Trichloroethylene induced cutaneous irritation in BALB/c hairless mice: histopathological changes and oxidative damage, Toxicology, vol.248, pp.113-120, 2008.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

, Assessing the human health risks of trichloroethylene: key scientific issues, 2006.

P. Kumar, A. K. Prasad, and K. K. Dutta, Steroidogenic alterations in testes and sera of rats exposed to trichloroethylene (TCE) by inhalation, Human and Experimental Toxicology, vol.19, pp.117-121, 2000.

P. Kumar, Trichloroethylene induced testicular toxicity in rats exposed by inhalation, Human and Experimental Toxicology, vol.20, pp.585-589, 2001.

H. Xu, Exposure to trichloroethylene and its metabolites causes impairment of sperm fertilizing ability in mice, Toxicological Sciences, vol.82, pp.590-597, 2004.

F. W. Kan, P. G. Forkert, and M. G. Wade, Trichloroethylene exposure elicits damage in epididymal epithelium and spermatozoa in mice, Histology and Histopathology, vol.22, pp.977-988, 2007.

T. Berger and C. M. Horner, In vivo exposure of female rats to toxicants may affect oocyte quality, Reproductive Toxicology, vol.17, p.447, 2003.

K. L. Wu and T. Berger, Trichloroethylene metabolism in the rat ovary reduces oocyte fertilizability, Chemico-Biological Interactions, vol.170, pp.20-30, 2007.

K. L. Wu and T. Berger, Reduction in rat oocyte fertilizability mediated by S-(1,2-dichlorovinyle)-L-cysteine: a trichloroethylene metabolite produced by the glutathione conjugation pathway, Bulletin of Environmental Contamination and Toxicology, vol.81, pp.490-493, 2008.

J. C. Lamb and K. L. Hentz, Toxicological review of male reproductive effects and trichloroethylene exposure: assessing the relevance to human male reproductive health, Reproductive Toxicology, vol.22, pp.557-563, 2006.

A. L. Williams and J. M. Desesso, Trichloroethylene and ocular malformations: analysis of extant literature, International Journal of Toxicology, vol.27, pp.81-95, 2008.

E. W. Carney, Developmental toxicity studies in Crl:CD (SD) rats following inhalation exposure to trichloroethylene and perchloroethylene, Part B, Developmental and Reproductive Toxicology, vol.77, pp.405-412, 2006.

S. J. Blossom, Developmental exposure to trichloroethylene promotes CD4+ T cell differentiation and hyperactivity in association with oxidative stress and neurobehavioral deficits in MRL+/+ mice, Toxicology and Applied Pharmacology, vol.231, pp.344-353, 2008.

P. Kjellstrand, Trichloroethylene: further studies of the effects on body and organ weights and plasma butylcholinesterase activity in mice, Acta Pharmacologica et Toxicologica, vol.53, pp.375-384, 1983.

K. Fukuda, K. Takemoto, and H. Tsuruta, Inhalation carcinogenicity of trichloroethylene in mice and rats, Industrial Health, vol.21, pp.243-254, 1983.

L. H. Lash, J. C. Parker, and C. S. Scott, Modes of action of trichloroethylene for kidney tumorigenesis, Environmental Health Perspectives, vol.108, pp.225-240, 2000.

, Trichloroethylene health risk assessment: synthesis and characterization (draft), 2001.

H. J. Clewell and M. E. Andersen, Applying mode-of-action and pharmacokinetic considerations in contemporary cancer risk assessments: an example with trichloroethylene, Critical Reviews in Toxicology, vol.34, pp.385-445, 2004.

R. J. Bull, Mode of action of liver tumor induction by trichloroethylene and its metabolites, Environmental Health Perspectives, vol.108, pp.241-259, 2000.

R. J. Bull, Contribution of dichloroacetate and trichloroacetate to liver tumor induction in mice by trichloroethylene, Toxicology and Applied Pharmacology, vol.182, pp.55-65, 2002.

, Report on carcinogens, 2005.

, Background document for development of WHO Guidelines for Drinking-water Quality. Geneva, World Health Organization, Trichloroethylene in drinking-water, 2005.

B. Charbotel, Trichloroethylene exposure and somatic mutations of the VHL gene in patients with Renal Cell Carcinoma, Journal of Occupational Medicine and Toxicology, vol.12, p.13, 2007.
URL : https://hal.archives-ouvertes.fr/hal-01681863

D. Henschler, Carcinogenicity study of trichloroethylene by long-term inhalation in three animal species, Archives of Toxicology, vol.43, pp.237-248, 1980.

, Trichloroethylene: assessment of human carcinogenic hazard. Brussels, European Centre for Ecotoxicology and Toxicology of Chemicals, 1994.

C. Hu, Possible involvement of oxidative stress in trichloroethyleneinduced genotoxicity in human HepG2 cells, Mutation Research, vol.652, pp.88-94, 2008.

P. Clay, Assessment of the genotoxicity of trichloroethylene and its metabolite, S-(1,2-dichlorovinyl)-L-cysteine (DCVC), in the comet assay in rat kidney, Mutagenesis, vol.23, pp.27-33, 2008.

M. Carrieri, Acute, nonfatal intoxication with trichloroethylene, Archives in Toxicology, vol.81, pp.529-532, 2007.

A. Takaki, A 27-year-old man who died of acute liver failure probably due to trichloroethylene abuse, Journal of Gastroenterology, vol.43, pp.239-242, 2008.

T. Nagaya, Subclinical and reversible hepatic effects of occupational exposure to trichloroethylene, International Archives of Occupational and Environmental Health, vol.64, pp.561-563, 1993.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

M. Kamijima, Trichloroethylene causes generalized hypersensitivity skin disorders complicated by hepatitis, Journal of Occupational Health, vol.50, pp.328-338, 2008.

X. Xu, Severe hypersensitivity dermatitis and liver dysfunction induced by occupational exposure to trichloroethylene, Industrial Health, vol.47, pp.107-112, 2009.

J. Liu, Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis, Toxicology and Applied Pharmacology, vol.240, pp.393-400, 2009.

S. E. Chia, Semen parameters in workers exposed to tcrichloroethylene, Reproductive Toxicology, vol.10, pp.295-299, 1996.

S. E. Chia, V. H. Goh, and C. N. Ong, Endocrine profiles of male workers with exposure to trichloroethylene, American Journal of Industrial Medicine, vol.32, pp.217-222, 1997.

V. H. Goh, S. E. Chia, and C. N. Ong, Effects of chronic exposure to low doses of trichloroethylene on steroid hormone and insulin levels in normal men, Environmental Health Perspectives, vol.106, pp.41-44, 1998.

P. D. Wilson, Attributable fraction for cardiac malformations, American Journal of Epidemiology, vol.148, pp.414-423, 1998.

C. Ferencz, Genetic and environmental risk factors of major cardiovascular malformations. The Baltimore-Washington Infant Study 1981-1989, 1997.

S. W. Lagakos, B. J. Wessen, and M. Zelen, Journal of the American Statistical Association, vol.81, pp.583-596, 1986.

S. H. Swan, Congenital cardiac anomalies in relation to water contamination, American Journal of Epidemiology, vol.129, pp.885-893, 1981.

F. J. Bove, Public drinking water contamination and birth outcomes, American Journal of Epidemiology, vol.141, pp.850-862, 1995.

S. E. Rodenbeck, L. M. Sanderson, and R. A. , Maternal exposure to trichloroethylene in drinking water and birth-weight outcomes, Archives of Environmental Health, vol.55, pp.188-194, 2000.

, Town of Union, Health statistics review: cancer and birth outcome analysis, 2005.

J. S. Yauck, Proximity of residence to trichloroethylene-emitting sites and increased risk of offspring congenital heart defects among older women. Birth Defects Research and Clinical Molecular Teratology, vol.70, pp.808-814, 2004.

A. Anttila, Cancer incidence among Finnish workers exposed to halogenated hydrocarbons, Journal of Environmental and Occupational Medicine, vol.37, pp.797-806, 1995.

M. L. Lindbohm, Risks of liver cancer and exposure to organic solvents and gasoline vapors among Finish workers, International Journal of Cancer, vol.124, pp.2954-2959, 2009.

O. Axelson, Updated and expanded Swedish cohort study on trichloroethylene and cancer risk, Journal of Occupational Medicine, vol.36, pp.556-562, 1994.

R. Spirtas, Retrospective cohort mortality study of workers at an aircraft maintenance facility. I. Epidemiological results, British Journal of Industrial Medicine, vol.48, pp.515-530, 1991.

A. Seidler, Solvent exposure and malignant lymphoma: a populationbased case-control study in Germany, Journal of Occupational Medicine and Toxicology, vol.2, pp.2-12, 2007.

C. S. Scott and W. A. Chiu, Trichloroethylene cancer epidemiology: a consideration of select issues, vol.114, pp.1471-1478, 2006.

J. H. Mandel, Occupational trichloroethylene exposure and non-Hodgkin's lymphoma: a meta-analysis and review, Occupational and Environmental Medicine, vol.63, pp.597-607, 2006.

D. D. Alexander, A meta-analysis of occupational trichloroethylene exposure and multiple myeloma or leukaemia, Occupational Medicine, vol.56, pp.485-493, 2006.

D. D. Alexander, A meta-analysis of occupational trichloroethylene exposure and liver cancer, International Archives of Occupational and Environmental Health, vol.81, pp.127-143, 2007.

D. Wartenberg, D. Reyner, and C. Siegel, Trichloroethylene and cancer: epidemiologic evidence, Environmental Health Perspectives, vol.10, pp.161-176, 2000.

T. A. Lewandowski and L. R. Rhomberg, A proposed methodology for selecting a trichloroethylene inhalation unit risk value for use in risk assessment, Regulatory Toxicology and Pharmacology, vol.41, pp.39-54, 2005.

G. Pastino, W. Yap, and M. Carroquino, Human variability and susceptibility to trichloroethylene, Environmental Health Perspectives, vol.108, pp.201-214, 2000.

T. Brüning, Renal cell cancer risk and occupational exposure to trichloroethylene: results of a consecutive case-control study in Arnsberg, Germany. American Journal of Industrial Medicine, vol.43, pp.274-285, 2003.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

B. Wiesenhütter, Re-assessment of the influence of polymorphisms of phase-II metabolic enzymes on renal cell cancer risk of trichloroethyleneexposed workers, International Archives of Occupational and Environmental Health, vol.81, pp.247-251, 2007.

C. Ruden, Interpretations of primary carcinogenicity data in 29 trichloroethylene risk assessments, Toxicology, vol.169, pp.209-225, 2001.

C. Ruden, The use and evaluation of primary data in 29 trichloroethylene carcinogen risk assessments, Regulatory Toxicology and Pharmacology, vol.34, pp.3-16, 2001.

N. Nijhuis and M. Loh,

, Tetrachloroethylene (PCE) (CAS Registry Number, pp.127-145

, Henry's Law constant 0.018 atm-m 3 /mol at 25 °C; log K ow (octanol/water partition coefficient) 3.40 (measurement value) and 2.97

, Tetrachloroethylene Common synonyms include perchloroethylene, PCE, ethylene tetrachloride, tetrachloroethene, 1,1,2,2-tetrachloroethylene, carbon dichloride, perchlor, tetrachloroethane, carbon bichloride, PERC, PCE and perk

, Hazardous Substances Data Bank (HSDB) [online database

M. D. Bethesda, , p.19, 2010.

, Agency for Toxic Substances and Disease Registry (ATSDR), 1997.

K. Verschueren, Handbook of environmental data on organic chemicals, 2001.

, KowWin Estimation Software, ver. 1.66. North, 2002.

, AopWin Estimation Software, ver. 1.90. North, 2002.

. Tetrachloroethylene, Priority substances assessment report for the Canadian Environmental Protection Act. Ottawa, Environment Canada and Health Canada, 1993.

P. H. Howard, Handbook of environmental degradation rates, 1991.

, Dry cleaning, some chlorinated solvents and other industrial chemicals. Summary of data reported and evaluation. Lyon, International Agency for Research on Cancer, Evaluation of Carcinogenic Risks to Humans, vol.63, 1995.

, Development of initial risk assessment method for chemical substances and preparation of the initial risk assessment, 2002.

V. Grote and J. , Reduction of occupational exposure to perchloroethylene and trichloroethylene in metal degreasing over the last 30 years: influences of technology innovation and legislation, Journal of Exposure Analysis and Environmental Epidemiology, vol.13, pp.325-340, 2003.

R. G. Lewis and S. M. Gordon, Sampling for organic chemicals in air, Principles of environmental sampling, pp.401-470, 1996.

T. I. Mudder and J. L. Musterman, Development of empirical structure biodegradability relationships and biodegradability testing protocol for volatile and slightly soluble priority pollutants. Abstracts of Papers of the, vol.184, p.18, 1982.

E. J. Bouwer, B. E. Rittmann, and P. L. Mccarty, Anaerobic degradation of halogenated 1-carbon and 2-carbon organic-compounds, Environmental Science & Technology, vol.15, pp.596-599, 1981.

, Report on environmental survey and wildlife monitoring of chemicals, Tokyo, Ministry of the Environment, 2001.

G. Aggazzotti, Indoor exposure to perchloroethylene (PCE) in individuals living with dry-cleaning workers, Science of the Total Environment, vol.156, pp.133-137, 1994.

. Tetrachloroethylene and . Geneva, World Health Organization, 1984.

T. Vartiainen, Population exposure to trichloroethene and tetrachloroethene and cancer risk -2 cases of drinking-water pollution, Chemosphere, vol.27, pp.1171-1181, 1993.

, Database of Water Quality of Aqueduct

. Tokyo, Japan Water Works Association, 2008.

J. L. Adgate, Outdoor, indoor, and personal exposure to VOCs in children, vol.112, pp.1386-1392, 2004.

J. L. Adgate, Personal, indoor, and outdoor VOC exposures in a probability sample of children, Journal of Exposure Analysis and Environmental Epidemiology, vol.14, pp.4-13, 2004.

C. A. Clayton, National Human Exposure Assessment Survey (NHEXAS): distributions and associations of lead, arsenic and volatile organic compounds in EPA Region 5, Journal of Exposure Analysis and Environmental Epidemiology, vol.9, pp.381-392, 1999.

D. C. Payne-sturges, Personal exposure meets risk assessment: a comparison of measured and modeled exposures and risks in an urban community, Environmental Health Perspectives, vol.112, pp.589-598, 2004.

S. N. Sax, Differences in source emission rates of volatile organic compounds in inner-city residences of, Journal of Exposure Analysis and Environmental Epidemiology, vol.14, pp.95-109, 2004.

K. Sexton, Comparison of personal, indoor, and outdoor exposures to hazardous air pollutants in three urban communities, Environmental Science & Technology, vol.38, pp.423-430, 2004.

M. R. Van-winkle and P. A. Scheff, Volatile organic compounds, polycyclic aromatic hydrocarbons and elements in the air of ten urban homes, Indoor Air, vol.11, pp.49-64, 2001.

C. P. Weisel, Relationship between indoor, outdoor and personal air (RIOPA). Houston, TX, Health Effects Institute and National Urban Air Toxics Research Center, 2005.

M. J. Mcdermott, Tetrachloroethylene (PCE, perc) levels in residential dry cleaner buildings in diverse communities in New York City, vol.113, pp.1336-1343, 2005.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

S. Kirchner, National dwellings survey: report on air quality in French dwellings, Final Report, Indoor Air Quality Observatory, 2006.

M. J. Jantunen, Air pollution exposure in European cities: the EXPOLIS Study. Kuopio, National Public Health Institute, 1999.

T. Ohura, Organic air pollutants inside and outside residences in Shimizu, Japan: levels, sources and risks, Science of the Total Environment, vol.366, pp.485-499, 2006.

, Report of the nationwide survey of indoor volatile organic chemicals in residential houses, Ministry of Health and Welfare, 1999.

J. Raisanen, R. Niemela, and C. Rosenberg, Tetrachloroethylene emissions and exposure in dry cleaning, Journal of the Air & Waste Management Association, vol.51, pp.1671-1675, 2001.

D. J. Moschandreas and D. S. Odea, Measurement of perchloroethylene indoor air levels caused by fugitive emissions from unvented dry-to-dry dry-cleaning units, Journal of the Air & Waste Management Association, vol.45, pp.111-115, 1995.

B. M. Eklund, Spatial and temporal variability in VOC levels within a commercial retail building, Indoor Air, vol.18, pp.365-374, 2008.

, Building Assessment Survey and Evaluation (BASE) Study, 2008.

C. Y. Chao and G. Y. Chan, Quantification of indoor VOCs in twenty mechanically ventilated buildings in Hong Kong, Atmospheric Environment, vol.35, pp.5895-5913, 2001.

M. M. Loh, Measured concentrations of VOCs in several non-residential microenvironments in the United States, Environmental Science & Technology, vol.4, pp.6903-6911, 2006.

X. I. You, Determinants of airborne concentrations of volatile organic compounds in rural areas of Western Canada, Journal of Exposure Analysis and Environmental Epidemiology, vol.18, pp.117-128, 2008.

L. Wallace, The Total Exposure Assessment Methodology (TEAM) study: summary and analysis, vol.1, 1987.

L. A. Wallace, W. C. Nelson, and R. Ziegenfus, The Los Angeles TEAM study: personal exposures, indoor-outdoor air concentrations, and breath concentrations of 25 volatile organic compounds, Journal of Exposure Analysis and Environmental Epidemiology, vol.1, pp.157-192, 1991.

C. E. Dallas, Use of physiologically based model to predict systemic uptake and respiratory elimination of perchloroethylene, Toxicology and Applied Pharmacology, vol.128, pp.60-69, 1994.

J. S. Nakai, Penetration of chloroform, trichloroethylene, and tetrachloroethylene through human skin, Journal of Toxicology and Environmental Health A, vol.58, pp.157-170, 1999.

T. S. Poet, PBPK modeling of the percutaneous absorption of perchloroethylene from a soil matrix in rats and humans, Toxicological Sciences, vol.67, pp.17-31, 2002.

. Tetrachloroethylene, Agency for Toxic Substances and Disease Registry, 2010.

R. P. Beliles, Concordance across species in the reproductive and developmental toxicity of tetrachloroethylene, Toxicology and Industrial Health, vol.18, pp.91-106, 2002.

C. E. Dallas, Development of a physiologically based model for perchloroethylene using tissue concentration-time data, Toxicology and Applied Pharmacology, vol.128, pp.50-59, 1994.

L. T. Mckernan, Biological exposure assessment to tetrachloroethylene for workers in the dry cleaning industry, Environmental Health, vol.7, p.12, 2008.

L. H. Lash and J. C. Parker, Hepatic and renal toxicities associated with perchloroethylene, Pharmacological Reviews, vol.53, pp.177-208, 2001.

L. H. Lash, Renal toxicity of perchloroethylene and S-(1,2,2-trichlorovinyl)glutathione in rats and mice: sex-and species-dependent differences, Toxicology and Applied Pharmacology, vol.179, pp.163-171, 2002.

B. K. Philip, Impact of repeated exposure on toxicity of perchloroethylene in Swiss Webster mice, Toxicology, vol.232, pp.1-14, 2007.

, Tetrachloroethylene: assessment of human carcinogenic hazard. Brussels, European Centre for Ecotoxicology and Toxicology of Chemicals, 1990.

T. Green, Perchloroethylene-induced rat kidney tumors: an investigation of the mechanisms involved and their relevance to humans, Toxicology and Applied Pharmacology, vol.103, pp.77-89, 1990.

L. H. Lash, Glutathione conjugation of perchloroethylene in rats and mice in vitro: sex-, species-, and tissue-dependent differences, Toxicology and Applied Pharmacology, vol.150, pp.49-57, 1998.

W. Völkel, Biotransformation of perchloroethene: dose-dependent excretion of trichloroacetic acid, dichloroacetic acid, and N-acetyl-S-(trichlorovinyl)-L-cysteine in rats and humans after inhalation, Toxicology and Applied Pharmacology, vol.153, pp.20-27, 1998.

T. Ohtsuki, Limited capacity of humans to metabolize tetrachloroethylene, International Archives of Occupational and Environmental Health, vol.51, pp.381-390, 1983.

F. Y. Bois, Population toxicokinetics of tetrachloroethylene, Archives of Toxicology, vol.70, pp.347-355, 1996.
URL : https://hal.archives-ouvertes.fr/ineris-00969532

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

W. A. Chiu, Toxicokinetics of inhaled trichloroethylene and tetrachloroethylene in humans at 1 ppm: empirical results and comparisons with previous studies, Toxicological Sciences, vol.95, pp.23-36, 2007.

J. Z. Byczkowski, Computer simulation of the lactational transfer of tetrachloroethylene in rats using a physiologically based model, Toxicology and Applied Pharmacology, vol.125, pp.228-236, 1994.

T. Hamada and H. Tanaka, Transfer of methyl chloroform, trichloroethylene and tetrachloroethylene to milk, tissues and expired air following intraruminal or oral administration in lactating goats and milk-fed kids, Environmental Pollution, vol.87, pp.313-318, 1995.

J. S. Schreiber, Predicted infant exposure to tetrachloroethylene in human breastmilk, Risk Analysis, vol.13, pp.515-524, 1993.

F. Gobba, Perchloroethylene in alveolar air, blood, and urine as biologic indices of low-level exposure, Journal of Occupational and Environmental Medicine, vol.45, pp.1152-1157, 2003.

R. Lauwerys, Health surveillance of workers exposed to tetrachloroethylene in dry-cleaning shops, International Archives of Occupational and Environmental Health, vol.52, pp.69-77, 1983.

K. Furuki, Monitoring of occupational exposure to tetrachloroethene by analysis for unmetabolized tetrachloroethene in blood and urine in comparison with urinalysis for trichloroacetic acid, International Archives of Occupational and Environmental Health, vol.73, pp.221-227, 2000.

C. W. Chen and J. N. Blancato, Role of pharmacokinetic modeling in risk assessment: perchloroethylene as an example, Pharmacokinetics in risk assessment -drinking water and health, vol.8, 1987.

K. T. Bogen and T. E. Mckone, Linking indoor air and pharmacokinetic models to assess tetrachloroethylene risk, Risk Analysis, vol.8, pp.509-552, 1988.

R. C. Ward, Pharmacokinetics of tetrachloroethylene, Toxicology and Applied Pharmacology, vol.93, pp.108-117, 1988.

A. Koizumi, Potential of physiologically based pharmacokinetics to amalgamate kinetic data of trichloroethylene and tetrachloroethylene obtained in rats and man, British Journal of Industrial Medicine, vol.46, pp.239-249, 1989.

C. E. Dallas, Use of tissue distribution data from rats and dogs to determine species differences in input parameters for a physiological model for perchloroethylene, Environmental Research, vol.67, pp.54-67, 1994.

C. E. Dallas, Physiologically based pharmacokinetic model useful in prediction of the influence of species, dose, and exposure route of perchloroethylene pharmacokinetics, Journal of Toxicology and Environmental Health, vol.44, pp.301-317, 1995.

J. Y. Jang and P. O. Droz, Ethnic differences in biological monitoring of several organic solvents. II. A simulation study with a physiologically based pharmacokinetic model, International Archives of Occupational and Environmental Health, vol.70, pp.41-50, 1997.

J. M. Gearhart, Variability of physiologically based pharmacokinetic (PBPK) model parameters and their effects on PBPK model predictions in a risk assessment for perchloroethylene (PCE), Toxicology Letters, vol.68, pp.131-144, 1993.

R. H. Reitz, In vivo and in vitro studies of perchloroethylene metabolism for physiologically based pharmacokinetic modeling in rats, mice, and humans, Toxicology and Applied Pharmacology, vol.136, pp.289-306, 1996.

I. D. Dobrev, M. E. Andersen, and R. S. Yang, Assessing interaction thresholds for trichloroethylene in combination with tetrachloroethylene and 1,1,1-trichloroethane using gas uptake studies and PBPK modeling, Archives of Toxicology, vol.75, pp.134-144, 2001.

G. D. Loizou, The application of physiologically based pharmacokinetic modelling in the analysis of occupational exposure to perchloroethylene, Toxicology Letters, vol.124, pp.59-69, 2001.

T. S. Poet, PBPK modeling of the percutaneous absorption of perchloroethylene from a soil matrix in rats and humans, Toxicological Sciences, vol.67, pp.17-31, 2002.

I. D. Dobrev, M. E. Andersen, and R. S. Yang, In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane, vol.110, pp.1031-1039, 2002.

H. J. Clewell, Evaluation of physiologically based pharmacokinetic models in risk assessment: an example with perchloroethylene, Critical Reviews in Toxicology, vol.35, pp.413-433, 2005.

W. A. Chiu and F. Y. Bois, Revisiting the population toxicokinetics of tetrachloroethylene, Erratum. Archives of Toxicology, vol.80, p.386, 2006.
URL : https://hal.archives-ouvertes.fr/ineris-00969532

T. R. Covington, The use of Markov chain Monte Carlo uncertainty analysis to support a Public Health Goal for perchloroethylene, Regulatory Toxicology and Pharmacology, vol.47, pp.1-18, 2007.

J. C. Ramsey and M. E. Andersen, A physiologically based description of the inhalation pharmacokinetics of styrene in rats and humans, Toxicology and Applied Pharmacology, vol.73, pp.159-175, 1984.

D. Hattis, Uncertainties in pharmacokinetic modelling for perchloroethylene. I. Comparison of model structure, parameters, and predictions for low-dose metabolism rates for models derived by different authors, Risk Analysis, vol.10, pp.449-458, 1990.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

F. Y. Bois, Precision and sensitivity of pharmacokinetic models for cancer risk assessment: tetrachloroethylene in mice, rats and humans, Toxicology and Applied Pharmacology, vol.102, pp.300-315, 1990.

P. Kjellstrand, Perchloroethylene: effects on body and organ weights and plasma butyrylcholinesterase activity in mice, Acta Pharmcologica et Toxicologica, vol.54, pp.414-424, 1984.

, Technical report on the toxicology carcinogenesis studies of tetrachloroethylene (perchloroethylene) in F344/N rats and B6C3F1 mice (inhalation studies), National Toxicology Program, issue.311, 1986.

H. Suzaki, A. Aoki, and Y. Nomura, Regeneration of olfactory mucosa in mice after inhalation exposure to perchloroethylene, Journal for Otorhinolaryngology and its Related Species, vol.59, pp.91-96, 1997.

S. Wang, Perchloroethylene-induced reduction of glial and neuronal cell marker proteins in rat brain, Pharmacology and Toxicology, vol.72, pp.273-278, 1993.

H. J. Seidel, Hematological toxicity of tetrachloroethylene in mice, Archives of Toxicology, vol.66, pp.228-230, 1992.

H. H. Chen, M. H. Chan, and S. H. Fu, Behavioural effects of tetrachloroethylene exposure in rats: acute and subchronic studies, Toxicology, vol.170, pp.201-209, 2002.

W. M. Oshiro, Q. T. Krantz, and P. J. Bushnell, Characterization of the effects of inhaled perchloroethylene on sustained attention in rats performing a visual signal detection task, Neurotoxicology and Teratology, vol.30, pp.167-174, 2008.

A. M. Saillenfait, I. Langonné, and J. P. Sabaté, Developmental toxicity of trichloroethylene, tetrachloroethylene and four of their metabolites in rat whole embryo culture, Archives of Toxicology, vol.70, issue.2, pp.71-82, 1995.

A. Fredriksson, B. R. Danielsson, and P. Eriksson, Altered behaviour in adult mice orally exposed to tri-and tetrachloroethylene as neonates, Toxicology Letters, vol.66, pp.13-19, 1993.

E. W. Carney, Developmental toxicity studies in Crl:CD (SD) rats following inhalation exposure to trichloroethylene and perchloroethylene, Birth Defects Research (Part B, vol.77, pp.405-412, 2006.

H. H. Chen, Effects of trichloroethylene and perchloroethylene on muscle contractile responses and epithelial prostaglandin release and acetylcholinesterase activity in swine trachea, Toxicological Sciences, vol.83, pp.149-154, 2005.

, 127-18-4) for possible carcinogenesis. Bethesda, MD, Department of Health, Education and Welfare, Technical report on the bioassay of tetrachloroethylene (CAS No, pp.77-813, 1977.

J. Ishmael and P. H. Dugard, A review of perchloroethylene and rat mononuclear cell leukemia, Regulatory Toxicology and Pharmacology, vol.45, pp.178-184, 2006.

, Dry cleaning, some chlorinated solvents and other industrial chemicals. Lyon, International Agency for Research on Cancer, Evaluation of Carcinogenic Risks to Humans, vol.63, 1997.

K. Murakami and K. Horikawa, The induction of micronuclei in mice hepatocytes and reticulocytes by tetrachloroethylene, Chemosphere, vol.31, pp.3733-3739, 1995.

L. Giovannini, Effect of ethanol chronic use on hepatotoxicity in rats exposed to tetrachloroethylene, International Journal of Tissue Reactions, vol.24, pp.281-285, 1992.

I. D. Dobrev, M. E. Andersen, and R. S. Yang, In silico toxicology: simulating interaction thresholds for human exposure to mixtures of trichloroethylene, tetrachloroethylene, and 1,1,1-trichloroethane, vol.110, pp.1031-1039, 2002.

C. Köppel, Acute tetrachloroethylene poisoning -blood elimination kinetics during hyperventilation therapy, Journal of Toxicology, Clinical Toxicology, vol.23, pp.103-115, 1985.

Y. H. Choi, ARF requiring hemodialysis after accidental perchloroethylene ingestion, American Journal of Kidney Diseases, vol.41, p.11, 2003.

B. Levine, A tetrachloroethylene fatality, Journal of Forensic Sciences, vol.26, pp.206-209, 1981.

R. Garnier, Coin-operated dry cleaning machines may be responsible for acute tetrachloroethylene poisoning: report of 26 cases including one death, Journal of Toxicology, Clinical Toxicology, vol.34, pp.191-197, 1996.

Y. Gaillard, F. Billault, and G. Pépin, Tetrachloroethylene fatality: case report and simple gas chromatographic determination in blood and tissues, Forensic Science International, vol.76, pp.161-168, 1995.

T. Lukaszewski, Acute tetrachloroethylene fatality, Clinical Toxicology, vol.15, pp.411-415, 1979.

B. Dehon, Tetrachloroethylene and trichloroethylene fatality: case report and simple headspace SPME-capillary gas chromatographic determination in tissues, Journal of Analytical Toxicology, vol.24, pp.22-26, 2000.

C. L. Hake and R. D. Stewart, Human exposure to tetrachloroethylene: inhalation and skin contact, Environmental Health Perspectives, vol.21, pp.231-238, 1977.

L. Altmann, Neurophysiological and psychological measurements reveal effects of acute low-level organic solvent exposure in humans, International Archives of Occupational and Environmental Health, vol.62, pp.493-499, 1990.

A. Seeber, Neurobehavioral toxicology of long-term exposure to tetrachloroethylene, Neurotoxicology and Teratology, vol.11, pp.579-583, 1990.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s,

C. Ferroni, Neurobehavioral and neuroendocrine effects of occupational exposure to perchloroethylene, Neurotoxicology, vol.13, pp.243-248, 1992.

H. Nakatsuka, Absence of blue-yellow color vision loss among workers exposed to toluene or tetrachloroethylene mostly at levels below occupational exposure limits, International Archives of Occupational and Environmental Health, vol.64, pp.113-117, 1992.

A. Cavalleri, Perchloroethylene exposure can induce color vision loss, Neuroscience Letters, vol.179, pp.162-166, 1994.

F. Gobba, Two-year evolution of perchloroethylene-induced colorvision loss, Archives of Environmental Health, vol.53, pp.196-198, 1998.

M. Onofrj, Optic neuritis with residual tunnel vision in perchloroethylene toxicity, Journal of Toxicology, Clinical Toxicology, vol.36, pp.603-607, 1998.

M. C. Perrin, Tetrachloroethylene exposure and risk of schizophrenia: offspring of dry cleaners in a population birth cohort, preliminary findings, Schizophrenia Research, vol.90, pp.251-254, 2007.

J. E. Storm and K. A. Mazor, Update of residential tetrachloroethylene exposure and decreases in visual contrast sensitivity, Environmental Health Perspectives, vol.112, p.980, 2004.

C. A. Brodkin, Hepatic ultrasonic changes in workers exposed to perchloroethylene, Occupational and Environmental Medicine, vol.52, pp.679-685, 1995.

A. Mutti, Nephropathies and exposure to perchloroethylene in drycleaners, Lancet, vol.340, pp.189-193, 1992.

A. J. Verplanke, M. H. Leummens, and R. F. Herber, Occupational exposure to tetrachloroethene and its effects on the kidneys, Journal of Occupational and Environmental Medicine, vol.41, pp.11-16, 1999.

I. Franchini, Early indicators of renal damage in workers exposed to organic solvents, International Archives of Occupational and Environmental Health, vol.52, pp.1-9, 1983.

N. Sonnenfeld, I. Hertz-picciotto, and W. E. Kaye, Tetrachloroethylene in drinking water and birth outcomes at the US Marine Corps Base at Camp Lejeune, North Carolina, American Journal of Epidemiology, vol.154, pp.902-908, 2001.

F. J. Bove, Public drinking water contamination and birth outcomes, American Journal of Epidemiology, vol.141, pp.850-862, 1995.

A. Chen and L. E. Sever, Comment on: Public drinking water contamination and birth outcomes, American Journal of Epidemiology, vol.143, pp.1179-1180, 1996.

J. L. Mills, Homocysteine metabolism in pregnancies complicated by neural-tube defects, Lancet, vol.345, pp.149-151, 1995.

P. A. Janulewicz, Risk of learning and behavioral disorders following prenatal and early postnatal exposure to tetrachloroethylene (PCE)-contaminated drinking water, Neurotoxicology and Teratology, vol.30, pp.175-185, 2008.

A. Aschengrau, Prenatal exposure to tetrachloroethylene-contaminated drinking water and the risk of adverse birth outcomes, Environmental Health Perspectives, vol.116, pp.814-820, 2008.

P. Doyle, Spontaneous abortion in dry cleaning workers potentially exposed to perchloroethylene, Occupational and Environmental Medicine, vol.54, pp.848-853, 1997.

J. Olsen, Low birthweight, congenital malformations, and spontaneous abortions among dry-cleaning workers in Scandinavia, Scandinavian Journal of Work and Environmental Health, vol.16, pp.163-168, 1990.

P. Kyyrönen, Spontaneous abortions and congenital malformations among women exposed to tetrachloroethylene in dry cleaning, Journal of Epidemiology and Community Health, vol.43, pp.346-351, 1989.

A. D. Mcdonald, Spontaneous abortion and occupation, Journal of Occupational Medicine, vol.28, pp.1232-1238, 1986.

M. G. Bosco, I. Figá-talamanca, and S. Salerno, Health and reproductive status of 24 female workers in dry cleaning shops, International Archives of Occupational and Environmental Health, vol.59, pp.295-301, 1987.

G. Ahlborg, Pregnancy outcome among women working in laundries and dry-cleaning shops using tetrachloroethylene, American Journal of Industrial Medicine, vol.17, pp.567-575, 1990.

M. Sallmén, Reduced fertility among women exposed to organic solvents, American Journal of Industrial Medicine, vol.27, pp.699-713, 1995.

, Volatile organic compounds in drinking water and adverse pregnancy outcomes, 1998.

, Research Triangle Park, NC, National Toxicology Program, pp.226-228, 2002.

M. Toraason, Effect of perchloroethylene, smoking, and race on oxidative DNA damage in female dry cleaners, Mutation Research, vol.539, pp.9-18, 2003.

C. Diodovich, Sensitivity of human cord blood cells to tetrachloroethylene: cellular and molecular endpoints, Archives of Toxicology, vol.79, pp.508-514, 2005.

A. Aschengrau, C. Paulu, and D. Ozonoff, Tetrachloroethylene-contaminated drinking water and the risk of breast cancer, vol.106, pp.947-953, 1998.

. W-h-o-g-u-i-d-e-l-i-n-e-s-f-o-r-i-n-d-o-o-r-a-i-r-q-u-a-l-i-t-y:-s-e-l-e-c-t-e-d-p-o-l-l-u-ta-n-t-s-139, A. Aschengrau, S. Rogers, and D. Ozonoff, Perchloroethylene-contaminated drinking water and the risk of breast cancer: additional results from Cape Cod, vol.111, pp.167-173, 2003.

V. Vieira, A. Aschengrau, and D. Ozonoff, Impact of tetrachloroethylenecontaminated drinking water on the risk of breast cancer: using a dose model to assess exposure in a case-control study, Environmental Health, vol.4, p.3, 2005.

C. Paulu, A. Aschengrau, and D. Ozonoff, Tetrachloroethylene-contaminated drinking water in Massachusetts and the risk of colon-rectum, lung, and other cancers, Environmental Health Perspectives, vol.107, pp.265-271, 1999.

K. A. Mundt, T. Birk, and M. T. Burch, Critical review of the epidemiological literature on occupational exposure to perchloroethylene and cancer, International Archives of Occupational and Environmental Health, vol.76, pp.473-491, 2003.

A. M. Ruder, Potential health effects of occupational chlorinated solvent exposure, Annals of the New York Academy of Sciences, vol.1076, pp.207-227, 2006.

, Human exposure characterisation of chemical substances, quantification of exposure routes. Ispra, Physical and Chemical Exposure Unit, 2005.

, Tetrachloroethylene (perchloroethylene), p.17, 2000.

. Department and . Health, Annual report of the Committees on Toxicity, Mutagenicity and Carcinogenicity of Chemicals in Food, Consumer Products and the Environment. London, The Stationery Office, 1997. 147. NIOSH pocket guide to chemical hazards, Tetrachloroethylene, pp.2005-149, 1996.

. Tetrachloroethylene, Air quality guidelines for Europe, 2000.

, Fax: +45 39 17 18 18 E-mail: contact@euro.who.int Web site, pp.45-84