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Bronchopneumopathie chronique obstructive Lait Cancer du pancréas Toxicity Bactérie Arsenic Inorganic arsenic Fibrose pulmonaire Drug–drug interactions Epidemiology Macrophages Farmer Efferocytosis Ruxolitinib Humans In vitro Apoptosis Genotoxicity Comorbidity Interstitial lung disease Immunotoxicity Cardiovascular diseases Carcinogens Dust exposure Dairy farmers Heterocyclic amines Cytokines Environmental risk factors Polarization Macrophage Bisphenol A Inflammatory diseases Detoxification Bacteria Diesel exhaust particles Scleroderma Toxicokinetics Exposition professionnelle Nrf2 Drug-drug interactions HepaRG cells Bretagne Immunité Inhibition Lung Pneumopathie infiltrante diffuse Drug transporters AhR COPD Pharmacokinetics France Dendritic cells GM-CSF Nintedanib Infection Docking Immunity Calcium Cytokine Hepatocytes Camp Whole lung lavage Inflammation Cancer Silica Diesel exhaust Cardiovascular Stress Polycyclic aromatic hydrocarbons Cytochrome P-450 Pesticides Granulocyte-macrophage colony-stimulating factor Regulation Idiopathic pulmonary fibrosis NF-κB Chest tube Benzoapyrene Cell signaling Crystalline silica Differentiation Hepatoma Risque professionnel Toxicité Human hepatocytes Cigarette smoke Air pollution Interleukin-8 Cytochrome P450 Chest tube drainage Hypertension artérielle pulmonaire Eleveurs de bétail Chronic obstructive pulmonary disease Drug transporter Gene expression Systemic sclerosis Aryl hydrocarbon receptor Hepatocyte Polycyclic aromatic hydrocarbon Pulmonary arterial hypertension Oxidative stress